basophilia


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basophilia

 [ba″so-fil´e-ah]
1. abnormal increase of basophils in the blood, seen in myxedema, hypothyroid conditions, ulcerative colitis, certain types of anemia, and other conditions. Called also basophilic leukocytosis.
2. the reaction of immature erythrocytes to basic dyes, so that they become blue or gray in color; stippling appears in lead poisoning.

ba·so·phil·i·a

(bā'sō-fil'ē-ă),
1. A condition in which there are more than the usual number of basophilic leukocytes in the circulating blood (basophilic leukocytosis) or an increase in the proportion of parenchymatous basophilic cells in an organ (in the bone marrow, basophilic hyperplasia).
2. A condition in which basophilic erythrocytes are found in circulating blood, as in certain instances of leukemia, advanced anemia, malaria, and plumbism. Synonym(s): Grawitz basophilia
3. The reaction of immature erythrocytes to basic dyes whereby the cells appear blue or contain bluish granules.
4. Beta adenohypophysis.
Synonym(s): basophilism

basophilia

(bā′sə-fĭl′ē-ə, -zə-)
n.
1. The affinity of cellular structures for basic dyes, such as methylene blue.
2. An increase in the number of basophils in the circulating blood.
3. An abnormal stippling of red blood cells with basic staining granules.

basophilia

Haematology
Basophilic leukocytosis
An increase in basophilic granulocytes in the peripheral blood.

Pathology
Having an affinity for basic dyes.

basophilia

Basophilic leukocytosis Hematology An absolute basophil count of > 100/mm3

ba·so·phil·i·a

(bā'sō-fil'ē-ă)
1. A condition in which there are more than the usual number of basophilic leukocytes in the circulating blood (basophilic leukocytosis) or an increase in the proportion of parenchymatous basophilic cells in an organ (in the bone marrow, basophilic hyperplasia).
2. A condition in which basophilic erythrocytes are found in circulating blood, as in certain instances of leukemia, advanced anemia, malaria, and lead poisoning.
3. The reaction of immature erythrocytes to basic dyes whereby the cells appear blue or contain bluish granules.
Synonym(s): basophilism.

basophilia

A rise in the proportion of BASOPHIL white cells in the blood. Punctate basophilia is a disorder of young red cells which show several deep blue dots on Romanowsky staining. This is a feature of any severe ANAEMIA but especially of BETA-THALASSAEMIA and lead poisoning.

Grawitz,

Paul, German pathologist, 1850-1932.
Grawitz basophilia - a condition in which basophilic erythrocytes are found in circulating blood, as in certain instances of leukemia, advanced anemia, malaria, and plumbism. Synonym(s): basophilia
Grawitz tumor - obsolete term for renal adenocarcinoma.

ba·so·phil·i·a

(bā'sō-fil'ē-ă)
A condition in which there are more than the usual number of basophilic leukocytes in the circulating blood (basophilic leukocytosis) or an increase in the proportion of parenchymatous basophilic cells in an organ (in the bone marrow, basophilic hyperplasia).
References in periodicals archive ?
Sugishima et al., "Overt leukemia from MDS associated with marked basophilia," The Japanese Journal of Clinical Hematology, vol.
Although the argument could be made that these small, pale cells represent tangential cuts of larger cells, it is clear that atrophy of myocytes is occurring since other myocytes in these hyalinized are as are also reduced in size--but to a lesser degree and with retention of normal nuclear basophilia. In addition, it would seem unlikely to have so many small, pale nuclei in one field as a result of tangential sectioning.
Such lesions exhibited marked cell basophilia and prominent nuclei with an evident nucleoli.
(10) Basophilia, eosinophilia and thrombocytosis are often present.
Toluidine blue (TB) is a basic dye that helps in identification of myeloid blasts showing differentiation towards basophils, which may be seen in acute basophilic leukemia, basophilic blast crisis of chronic myeloid leukemia (CML) and AML with basophilia. Reactivity for TB is not seen in lymphoblasts.
The degenerative changes extend to the level of the perichondrium; they are associated with (1) a loss of the normal basophilia of the underlying cartilage, (2) focal fibrosis with increased cellularity, or (3) dropout of chondrocytes.
Associated basophilia and thrombocytosis are common.
They also reported that kidneys showed treatment-related increases in [[alpha].sub.2][mu]-globulin (an effect not observed with TCE treatment) along with hyaline droplet accumulation and basophilia between 16 and 18 weeks but gave no quantitative analyses.
Sections through the abdomens of lycosid females after staining with Azure B reveal large amounts of RNA basophilia present in cells of the midgut diverticula (MGD) that fill the space around and under the heart chamber, which is positioned just below the dorsal surface of the body (HC in Fig.
An increase in the basophil count (basophilia) occurs in chronic inflammatory and hypersensitivity reactions.
Basophilia is often prominent and is very helpful in separating this disorder from other causes of leukocytosis.
The principal histologic change observable in fetal organs after death is disappearance of nuclear basophilia, or staining characteristics The pathologist tests for this loss using a process that stains the cell Because the nucleus disintegrates when a cell dies, there will be less basophilia staining present in a dead cell than in a living one.(20)