baseline imbalance

baseline imbalance

A term of art for a systematic error in creating intervention groups in a clinical trial, such that participants differ with respect to prognosis—i.e., the groups differ in baseline characteristics because of the way in which the participants were selected or assigned—or because the participants are not representative of the population from which they were selected.
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The same trend of the baseline imbalance condition for the second bank is obtained in this test which shows the consistency of the estimates across different conditions.
This is supported by marked baseline imbalance in the numbers of patients that received crystalloids and colloids in the 12 h prior to randomization.
Available observed data on univariate associations were presented, with no imputation of missing data or adjustment for baseline imbalances.
'Adding to the several analyses in the literature that attempt to use traditional means to take into account baseline imbalances in (the NINDS-TPA trials), this entirely complementary and novel approach of sliding dichotomy also shows robust treatment effects," Dr.
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