base-substitution mutation

base-substitution mutation

A point mutation resulting in the replacement of one nitrogenous base in DNA for another.
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In addition, adriamycin can also induce frameshift and/or base-substitution mutations in prokaryotic (McCann et al.
THE INDUCTION OF GC TO AT TRANSITION MUTATIONS WITH ADRIAMYCIN IN THE BACTERIUM SALMONELLA TYPHIMURIUM
Thus, it appears that daunomycin can induce a wide array of mutational events which include frameshifts and base-substitution mutations.
Prior to this study, it was not known if daunomycin could induce base-substitution mutations.
The mutagenic effects of anthracyclines in the bacterium Salmonella typhimurium: induction of transition mutations with daunomycin

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