base deletion

base deletion

removal of a NUCLEOTIDE base, a purine or a pyrimidine from the DNA structure, producing a DELETION MUTATION that can have serious consequences for the related protein. See FRAMESHIFT.
References in periodicals archive ?
The exonic single base deletion mutations in patients FA82, FA121 and FA199 all resulted in frameshift mutations.
The scientists sequenced two of those genes in their patients and identified a single base deletion in all four patients.
The frequency of base substitution and small deletions including single base deletions and deletions < 1 kb formed in fiber-treated MEF cells was only 2-fold higher than those from nontreated cases.