basal cell


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ba·sal cell

a cell of the deepest layer of stratified epithelium.
Synonym(s): basilar cell

basal cell

n.
A type of cell found in the deepest layer of the epithelium.

basal cell

A relatively undifferentiated epithelial cell, which gives rise to more specialised cells.
 
Dermatology
In the stratified squamous epithelium of the skin, the basal cells of the epidermis (stratum basale) give rise by unequal division to other basal cells (BCs) and to cells that progress through the spinous, granular and horny layers, becoming increasingly keratinised; the outermost cells eventually slough as squames.

Olfaction
In the olfactory mucosa, BCs give rise to olfactory and sustentacular cells.

Urology
In epididymal cells, the function of BCs is unclear; they likely serve as urothelial stem cells.

ba·sal cell

(bā'săl sel)
A cell of the deepest layer of stratified epithelium.

basal cell

A cell of the single-cell-thick lowest layer of epithelia, such as the epidermis of the skin, from which all the more superficial layers are derived by MITOSIS.

ba·sal cell

(bā'săl sel)
Cell of the deepest layer of stratified epithelium.
References in periodicals archive ?
Reevaluating Mohs surgery appropriate use criteria for primary superficial basal cell carcinoma.
- Therapies in the pipeline for basal cell carcinoma focus on a wide variety of targets.
Polypoid basal cell carcinoma on the perianal region: A case report and review of the literature.
Another study from 24 centers in Japan24, it was reported that basal cell carcinoma has the highest incidence and accounts for almost 50% of the skin malignancies, followed by squamous cell carcinoma (31%), however, had a significantly raised frequency of malignant melanoma (21%), which was quite higher as compared to our study.
The most important key feature of basal cell carcinoma at low power magnification are that the basaloid epithelial cells of the tumour arising from the epidermis.
Malignant melanoma within squamous cell carcinoma and basal cell carcinoma: is it a combined or collision tumor?--a case report and review of the literature.
The importance of talking precautions (e.g., sun protection due to the high risk of basal cell carcinomas) and regular medical surveillance (e.g., regular orthodontic care and annual dermatologic examinations) was emphasized.
Immunohistochemistry should be performed additionally to routine histopathology in order to differentiate basal cell carcinoma from squamous cell carcinoma (SCC) of the skin or from basosquamous carcinoma, which presents a mixture of squamous and basaloid components.
Book, "Basal cell carcinoma: pathogenesis, epidemiology, clinical features, diagnosis, histopathology, and management," The Yale Journal of Biology and Medicine, vol.
Lapouge et al., "Identification of the cell lineage at the origin of basal cell carcinoma," Nature Cell Biology, vol.
Basal cell adenocarcinoma is generally described as a low-grade malignancy and prognosis is usually good.

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