baroreflex failure

baroreflex failure

A constellation of clinical findings characterised by marked lability of blood pressure with systolic/diastolic hypertension and tachycardia, ± headache, diaphoresis, emotional lability and refractoriness of heart rate in response to exogenous vasoactive substances alternating with hypotension and bradycardia.
 
Management
Clonidine suppresses pressor and tachycardic surges; diazepam reduces stress.

baroreflex failure

Physiology A constellation of clinical findings characterized by marked lability of BP with systolic/diastolic HTN and tachycardia, ± headache, diaphoresis, emotional lability, and refractoriness of heart rate in response to exogenous vasoactive substances alternating with hypotension and bradycardia Management Clonidine suppresses pressor and tachycardic surges, diazepam, reduces stress. Cf Autonomic failure.
References in periodicals archive ?
Autonomic failure in PD, therefore, seems to reflect a "triple whammy" of cardiac and extra-cardiac noradrenergic denervation and baroreflex failure. [19] Patients of PD did not show a significant drop in BP on tilt-up to define them as cases of OH.
In addition, patients with baroreflex failure suffer from a volatile hypertension with sympathetic nerve activity increased for years [33].
Sanchez-Ferro, Benito-Leon, and Gomez-Esteban (2013) add that a positive tilt table test with the patient positioned at least 60 degrees, complaining of orthostatic symptomatology, such as lightheadedness or dizziness, is also a positive sign of orthostatic hypotension (Fereshtehnejad & Lokk, 2014).The purpose of the tilt table test is to determine if there is arterial baroreflex failure in the heart (Fereshtehnejad & Lokk, 2014).
NOH is characterized by baroreflex failure in the heart that results in cerebral hypoperfusion, manifested by difficulty thinking and lightheadedness (Figueroa et al., 2010).
Radiation induced cranial neuropathies manifesting as baroreflex failure and progressive bulbar impairment.
Baroreflex failure syndrome after bilateral excision of carotid body tumors: an underestimated problem.