barbituric acid


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barbituric acid

 [bahr″bi-tu´rik]
the parent substance of the barbiturates, not itself a central nervous system depressant.

bar·bi·tu·ric ac·id

(bar'bi-chūr'ik as'id),
A crystalline dibasic acid from which barbital and other barbiturates are derived; has no sedative action.
Synonym(s): malonylurea

barbituric acid

/bar·bi·tur·ic ac·id/ (bahr-bĭ-tūr´ik) the parent substance of the barbiturates, not itself a central nervous system depressant.

barbituric acid

(bär′bĭ-to͝or′ĭk, -tyo͝or′-)
n.
An acidic pyrimidine derivative, C4H4O3N2, used in the manufacture of barbiturates and some plastics.

bar·bi·tu·ric ac·id

(bar'bi-chūr'ik as'id)
A nonsedating crystalline dibasic acid from which barbital and other barbiturates are derived.

barbituric acid

a compound, C4H4N2O3, the parent substance of barbiturate.
References in periodicals archive ?
9], quantitative variants of the Konig reaction with barbituric acid as the condensing reagent performed as well among our diabetic patients as among other previously studied groups.
The direct barbituric acid assay for nicotine metabolites in urine: a simple colorimetric test for routine assessment of smoking status and cigarette intake.
Diversity in biological activities of barbituric acid and its analogs have attracted the interest of medicinal chemists for exploring these molecules extensively.
Over 2500 derivatives of barbituric acid have been synthesized after the triumph of barbital and phenobarbital in epilepsy.
Eighteen derivatives (1-18) were synthesized from commercially available barbituric acid by condensation with various aldehydes at 100 degC in water.
Barbituric acid itself is hypnotically inactive, but substitution at C-5 of the barbiturate ring makes these analogs active as central nervous system depressants.
In the present study, we synthesized a series of N,N'-dimethylbarbituric acid derivatives 1-24, structurally close to allopurinol (25), with one of its rings resembled to barbituric acid (Fig.
The basic hypothesis was that an amide bond and a six member aromatic ring in the allupurinol and barbituric acid, respectively, may exhibit inhibitory potential against the xanthine oxidase.
Barbiturates are 2,4,6-trioxypyrimidine derivatives of barbituric acid.
As a further extension of this strategy, we now wish to report a convenient synthesis of 5-arylidene -barbiturates 3a-3s by way of a one pot Knoevenagel condensation between a variety of aromatic aldehydes 1a - 1s with barbituric acid 2 under solvent free conditions in presence of a catalytic amount of acetic acid (Scheme-1).