balsalazide


Also found in: Wikipedia.

balsalazide

 [bal-sal´ah-zīd]
a prodrug of the antiinflammatory mesalamine, to which it is converted in the colon; administered orally as the disodium salt in the treatment of ulcerative colitis.

balsalazide

/bal·sal·a·zide/ (bal-sal´ah-zīd) a prodrug of the antiinflammatory mesalamine, to which it is converted in the colon; administered orally as the sodium salt in the treatment of ulcerative colitis.

balsalazide

[bal-sal′ah-zīd]
a prodrug of the antiinflammatory mesalamine, to which it is converted in the colon; administered orally as the disodium salt in the treatment of ulcerative colitis.

balsalazide

Colazal® Internal medicine An agent that delivers concentrated 5-aminosalicylic acid to the colonic mucosa in Pts with ulcerative colitis. See Ulcerative colitis.

balsalazide

A drug used in the treatment of ULCERATIVE COLITIS. A brand name is Colazide.
Mentioned in ?
References in periodicals archive ?
Aminosalicylates, such as mesalamine (Lialda), mesalamine extended-release (Apriso), olsalazine (Dipentum), and balsalazide (Colazal)
Common aminosalicylates used in IBD include sulfasalazine, balsalazide, mesalamine, and olsalazine.
Children were defined as having IBD if they had either three or more health care visits for Crohn's disease or ulcerative colitis during the study's time frame, or "at least one health care contact for Crohn's disease or ulcerative colitis and at least one pharmacy claim for any of the following medications: mesalamine, olsalazine, balsalazide, sulfasalazine, 6-mercaptopurine, azathioprine, methotrexate, enteral budesonide, or biologies (infliximab, adalimumab, certolizumab, or natalizumab).
He had been maintained on balsalazide (5-ASA), metronidazole, adalimumab, and omeprazole.
This group includes mesalamine, or 5-aminosalicylic acid (5-ASA), sulphasalazine, olsalazine, and balsalazide.
The prodrugs sulfasalazine, olsalazine and balsalazide rely on colonic bacterial enzymes to metabolize the inactive precursor to the active drug mesalazine.
has announced the introduction of balsalazide disodium capsules, 750 mg.
Balsalazide tablets, Granulated Mesalamine and SANVAR (600 ug vials vapreotide acetate powder) are under development.
Two other agents in this class, balsalazide (Colazal) and olsalazine (Dipentum), are broken down in the colon to 5-ASA.
Three medicines are used for treating an acute attack: Aminosalicylates (such as balsalazide, mesalazine, olsalazine, sulfasalazine), Corticosteroids (budesonide, hydrocortisone, prednisolone) and Immunosuppressants (azathioprine, ciclosporin, mercaptopurine) Rest is important during an attack to allow healing to take place.
Balsalazide and azathioprine or 6-mercaptopurine: evidence for a potentially serious drug interaction.
Active UC should be treated initially with systemic aminosalicylate drugs (such as sulfasalazine, olsalazine, balsalazide, and mesalamine) or with corticosteroids.