Feeding behaviour of infected larvae determines the extent to which
baculoviruses can protect crops against feeding damage (Hoover et al., 1995).
Specificity and safety of
baculoviruses. In: The biology of
baculoviruses.
The vesicles are probably formed with membranous material found in the ring zone as in
baculoviruses. A viral nucleosome is also observed as a filamentous structure in the virogenic stroma.
The biology of
baculoviruses. Florida: CRC Press, 1986.
Because
baculoviruses evolved to infect insect cells, human cells don't recognize the promoter sequences within their genome, so those genes are not expressed and the virus can't replicate.
In sections on DNA viruses, RNA viruses, and current topics, they discuss such matters as entomopoxviruses, the biology and genetics of nudiviruses, the genomics and biology of iflavilruses, cypoviruses, the role of microRNAs as regulators of host-virus interactions, apoptosis and humeral responses as antiviral responses in insects, and the ecology of
baculoviruses. The focus is on damage to commercially valuable insects, primarily bees and silkworms, rather than using viruses for insect pest control, or insects as vectors for viruses affecting humans or livestock.
In another approach, biotechnologists are studying
baculoviruses, a large variety of viruses composed of double strands of DNA that act specifically on hundreds of arthropods, including many agricultural pests, but appear to be safe for plants and vertebrates.
Baculoviruses, a family of large rod-shaped viruses that typically infect insects, but do not replicate in vertebrate animal cells, are among the most promising.
We fused 2 different
baculoviruses (wild-type and recombinant) plus 2 influenza A viruses with color-coded microparticles and performed multiplexed fluorescence-activated cell-sorting (FACS) [3] titrations with specific antibodies and sera, and compared the results with results from ELISA.
Previous studies have shown the usefulness of BEI as an effective inactivating agent for
Baculoviruses. The goal of this study was to develop a method for the complete and rapid inactivation of a recombinant baculovirus (rBV) used in a veterinary vaccine.
Such
baculoviruses can be used to efficiently deliver genes to mammalian cells or organisms, and such genes can be expressed either from the baculovirus genome, or integrated into the mammalian cell genome, and can be used for expression of proteins such that purification of secreted or other protein products does not require removal of contaminating baculovirus particles or baculovirus envelope proteins.
Baculoviruses are rod-shaped DNA viruses, many of which begin their life cycle reproducing inside cells.