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A virus that infects insect cells; used extensively in expression systems for recombinant proteins that require eukaryotic processing systems.
[L. baculum, rod, + virus]
Farlex Partner Medical Dictionary © Farlex 2012


(băk″ū-lō-vī′rŭs) [L. baculum, staff, walking stick + ″]
A double-stranded DNA virus that infects insects. It has been used experimentally in recombinant DNA technology, e.g., in manufacturing vaccines.
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
Sf9 cells were seeded into 1000 mL cell culture flasks at a density of 2 x 10 cells/mL and infected with the P2 recombinant baculovirus rBac-VP1, rBac-VP1-gp120, or rBac-VP1-E2 when the cells were in the logarithmic phase.
Unlike most lepidopteran baculoviruses, Hymenoptera baculovirus can only replicate in the epithelial cells in the midgut of larvae.
The eukaryotic baculovirus expression system is characterized by an extensive array of posttranslational processing, typical for higher eukaryotic cells.
Jarvis, "Baculovirus as versatile vectors for protein expression in insect and mammalian cells," Nature Biotechnology, vol.
Prevalencia de Baculovirus penaei PsSOV Bonami (antes BP) en camarones peneidos cubanos silvestres.
Estas incluyen dentro de sus excipientes un protector UV que pertenece al grupo de los abrillantadores opticos; este grupo de compuestos, ademas de brindar fotoproteccion, ha mostrado tener un efecto potenciador de la actividad insecticida de varios baculovirus (Caballero et al.
Many viruses, such as Lentivirus, Adeno-Associated Virus (AAV), RetroVirus & Gamma RetroVirus, Modified Herpes, Simplex Virus, Adenovirus, Vaccinia virus, Baculovirus (Bacmid) are being modified and being researched upon to identify ideal vectors to deliver gene therapy drugs.
The Flublok proteins are manufactured in insect cells using a genetically engineered baculovirus.
Among the topics are the widespread occurrence and potential biological roles of endogenous viral elements in insect genomes, sensing viral infections in insects: a dearth of pathway receptors, looking through the lens of 'omics technologies: insights into the transmission of insect vector-borne plant viruses, developments in tetravirus research: new insight into the infectious virus life cycle and an expanding host range, recent developments in the use of baculovirus expression vectors, and baculovirus as versatile vectors for protein display and biotechnological applications.
So, selection for fast-acting baculovirus strains is an attractive option.

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