and cytologic criteria for diagnosis in nasal and sinus disease: Basis and interpretation.
results (absence of isolation of B.
cure was defined as the absence of growth of a predominant bacterial pathogen (cultured at baseline) in a sputum sample taken on day 10.
The topical group had a clinical response rate of 100% and a bacteriologic
cure rate of 95%, and the topical/oral group had rates of 95 and 85%, respectively.
* OUTCOMES MEASURED Primary study outcomes were bacteriologic
and clinical cures at a visit 4 to 11 days post-therapy, as determined by urine culture and signs and symptoms, respectively.
Therefore, the implementation of bacteriologic
diagnosis should be considered even in smaller hospitals in a rural African setting to monitor pathogen distribution and resistance rates.
Nevertheless, the prevailing treatment for AOE is still a topical antibiotic that (1) can be delivered at extremely high concentrations directly to the site of infection, (2) is bactericidal, and (3) can facilitate a rapid clinical and bacteriologic
cure, thereby preventing a secondary complication (e.g., cellulitis or middle ear and mastoid involvement).
Also, 84.4% of the ciprofloxacin group experienced bacteriologic
eradication, compared with 78.3% of the cephalosporin group.
The analysis suggests that fluoroquinolones are associated with an improved likelihood of clinical success and bacteriologic
eradication, but are not necessarily associated with lower mortality or a lower risk of an adverse event, Dr.
Outcomes measured Outcomes measured included clinical symptoms and signs (fever, tonsillar exudate, cervical lymphadenitis, throat pain), eradication of GABHS within 18 to 24 hours, and bacteriologic
treatment failure rate at 4 to 6 and 14 to 21 days.
Determination of infectiousness should be based on assessment of both clinical and bacteriologic
response to therapy ([6,7]; CDC, unpublished data).
bovis infection and describe the epidemiologic, clinical, and bacteriologic