Based on the experimental results, the release of bacteriocin
from nanofibers and its antibacterial activity significantly reduce the number of bacteria.
A number of bacteriocins
have been described for Lactobacillus (L.
They were insensitive to lipase and [alpha]-amylase, which eliminates the possibility that synthesized bacteriocins
are included in the group of complex biologically active substances containing a lipid or carbohydrate component (Mechai et al.
Competitive interactions in Escherichia coli populations: The role of bacteriocins
The interest in bacteriocins
produced by GRAS microorganisms has been leading to considerable interest for nisin, being the first bacteriocin
to gain widespread commercial application since 1969.
29) As mentioned earlier, it is thought that Usp is a nuclease-type bacteriocin
and OrfU proteins are immunity proteins for Usp based on sequence homology.
Isolates expressing bacteriocins
excrete proteins that inhibit the growth of closely related strains of bacteria, allowing the bacteriocin
-expressing isolate to out compete bacteriocin
sensitive strains for limited resources (DeVuyst et al, 2003; Franz et al.
AvidBiotics antibacterial technology is based on R-type bacteriocins
(proteins with bactericidal activity).
Similar results had been seen with bacteriocins
where activity requires a complementary peptide (Anderssen et al.
and fatty acids are just two examples of pharmabiotic substances which may contribute to probiotic functionality within the mammalian GIT.
are thought to maintain or regulate the mucus-membrane microbial ecosystem by production of antimicrobial substances such as bacteriocins
(Jack et al.
In the future, expect to learn about nisin's activity in combination with chelators and other bacteriocins
, and its use as an adjunct in novel food processing techniques, such as higher- pressure sterilization.