bacille Calmette-Guerin


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bacille

 [bah-sēl]
bacille Calmette-Guērin (BCG) Mycobacterium bovis that has been rendered completely avirulent by cultivation over a long period on bile-glycerol-potato medium. See also bcg vaccine and BCG solution.

ba·cil·le Cal·mette-Gué·rin (BCG),

(bah-sēl' kahl-met' gā-rĭn[h]'),
An attenuated strain of Mycobacterium bovis used in the preparation of BCG vaccine that is used for immunization against tuberculosis and in cancer chemotherapy.
Synonym(s): Calmette-Guérin bacillus
[Fr.]

bCG

Bacille Calmette-Guerin. A strain of Mycobacterium bovis which has been grown multiple generations on potato bile glycerine agar, to a point where the strain is not regarded as pathogenic. It is used to nonspecifically stimulate the immune response in patients with certain malignancies—e.g., melanoma.

BCG

Abbreviation for:
Bacillus Calmette-Guérin (Medspeak-UK)  
bromcresol green
bronchocentric granulomatosis

ba·cil·le Cal·mette-Gué·rin

(BCG) (bah-sēl' kahl-met' gā-răn[h]')
An attenuated strain of Mycobacterium bovis used in the preparation of BCG vaccine, which is used for immunization against tuberculosis and leprosy and in cancer chemotherapy.
Synonym(s): Calmette-Guérin bacillus.
[Fr.]

Calmette,

Leon Charles Albert, French bacteriologist, 1863-1933.
Bacille bilié de Calmette-Guérin - an attenuated strain of Mycobacterium bovis used for immunization against tuberculosis and in cancer chemotherapy. Synonym(s): Bacille Calmette-Guérin; Calmette-Guérin bacillus
Bacille Calmette-Guérin - Synonym(s): Bacille bilié de Calmette-Guérin
bacillus Calmette-Guérin vaccine - a vaccine for tuberculosis prophylaxis. Synonym(s): BCG vaccine
Calmette test - conjunctival reaction to tuberculin.
Calmette-Guérin bacillus - Synonym(s): Bacille bilié de Calmette-Guérin
Calmette-Guérin vaccine - Synonym(s): bacillus Calmette-Guérin vaccine

Guérin,

Camille, French bacteriologist, 1872-1961.
Bacille bilié de Calmette-Guérin - see under Calmette
Bacille Calmette-Guérin - Synonym(s): Bacille bilié de Calmette-Guérin
bacillus Calmette-Guérin vaccine - see under Calmette
Calmette-Guérin bacillus - Synonym(s): Bacille bilié de Calmette-Guérin
Calmette-Guérin vaccine - Synonym(s): bacillus Calmette-Guérin vaccine
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References in periodicals archive ?
Intravesical bacille Calmette-Guerin versus mitomycin C in superficial bladder cancer: formal meta-analysis of comparative studies on tumor progression.
Intravesical Therapies in Non-muscle Invasive Bladder Tumors
Role of needle aspiration in diagnosis and management of suppurative Bacille Calmette-Guerin adenitis: An institutional study of 30 cases.
Bacille Calmette-Guerin lymphadenitis in infants: A lesser known entity - Report of two cases
A human challenge model for Mycobacterium tuberculosis using Mycobacterium bovis bacille Calmette-Guerin. J Infect Dis 205, 1035-1042.
Replacing, reducing and refining the use of animals in tuberculosis vaccine research
Marsh, "The persistence of bacille Calmette-Guerin in the bladder after intravesical treatment for bladder cancer," British Journal of Urology, vol.
Tuberculous Spondylitis following Intravesical Bacillus Calmette-Guerin for Bladder Cancer
Five-year results of a phase II study with low-dose bacille Calmette-Guerin therapy in high-risk superficial bladder cancer.
CUA guidelines on the management of non-muscle invasive bladder cancer
Bacille Calmette-Guerin (BCG), an attenuated strain of Mycobacterium bovis, is (or has been) used as a routine childhood immunization in many parts of the world, although not in the United States.
Tuberculosis testing: which patients, which test?
Pathologic findings for bacille Calmette-Guerin infections in immunocompetent and immunocompromised patients.
Disseminated cutaneous BCG infection following BCG immunotherapy in patients with lepromatous leprosy
The immunological effect of revaccination with Bacille Calmette-Guerin vaccine at 19 months of age.
Nonspecific effects of vaccination
In 2008 the American College of Surgeons recognized Morton's "pioneering work" with intratumoral Bacille Calmette-Guerin (BCG) for nonspecific melanoma, the first successful clinical application of immunotherapy against a metastatic human cancer.
The WVSMA remembers our esteemed colleagues ..
Progression to muscle invasive disease increases to almost 50% in recurrent high grade tumors at 5 years.4,5 The mainstay of treatment for high grade NMIBC is intravesical Bacille Calmette-Guerin (BCG) therapy after transurethral resection, however in selected cases and BCG non-responders radical cystectomy is recommended.6 Other intra-vesical agents are also being used but none has surpassed the efficacy of BCG.7,8 It acts by inducing cytokine and direct cell to cell cytotoxicity response which targets tumor cells.
Factors affecting recurrence and progression of high grade non invasive bladder cancer treated by intravesical BCG
Furthermore, Qiagen's product decreases false-positive readings caused by the Bacille Calmette-Guerin (BCG) vaccination, which all newborns in China receive as a matter of policy.
Qiagen introduces QuantiFERON-TB blood test in China
Abbreviations PBST: PBS-Tween 80 BCG: Bacille Calmette-Guerin BCC-C: The group immunized with vaccine BCG-China substrain BCG-P: The group immunized with vaccine BCG-Pasteur1173 substrain BCG-C + pcDNA3.1: The group immunized BCG-China prime plasmid pcDNA3.1 boost BCG-P+pcDNA3.1: The group immunized BCG-Pasteur1173 prime plasmid pcDNA3.1 boost BCG-C+3.1-69: The group immunized BCG-China prime plasmid pcDNA3.1-Rv1769 boost BCG-P+3.1-69: The group immunized BCG-Pasteur1173 prime plasmid pcDNA3.1-Rv1769 boost BCG-C+3.1-72: The group immunized BCG-China prime plasmid pcDNA3.1-Rv1772 boost BCG-P+3.1-72: The group immunized BCG-Pasteur1173 prime plasmid pcDNA3.1-Rv1772 boost.
A Mycobacterium bovis BCG-naked DNA prime-boost vaccination strategy induced [CD4.sup.+] and [CD8.sup.+] T-cell response against Mycobacterium tuberculosis immunogens

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