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Related to b-lactam: Cephalosporins


A class of broad-spectrum antibiotics that are structurally and pharmacologically related to the penicillins and cephalosporins.


(bā′tə-lăk′təm, bē′-)
1. A lactam composed of a four-membered ring, formed by intramolecular condensation of an amino acid in which the amino group is located at the beta position, or any compound containing this group.
2. A beta-lactam antibiotic.


(bā'tă lak'tam)
Class of broad-spectrum antibiotics structurally and pharmacologically related to penicillins and cephalosporins.
References in periodicals archive ?
This kind of drug resistance is common in bacteria, which is dependent on b-lactam antibiotics rather than [beta]-lactamases (27).
The current study was planned to observe the AmpC b-lactamases which limits the therapeutic options for infections caused by gram-negative organisms and are usually resistant to all the b-lactam antibiotics.
In conclusion, the drug resistance is directly related to the clinical use time and range of b-lactam antibiotics.
This is a big problem in studying b-lactam resistance, as b-lactam resistance can increase due to inappropriate b-lactam use.
All cephelosporins and other b-lactam antibiotics were highly resistant (83-100%), except piperacillin/tazobactam with 42.6% resistance.
According to them, b-lactam resistance is widespread among Coliform bacteria due to vertical as well as horizontally acquired resistance factors.
In approximately 73% of the patients, the infecting strain of MRSA was resistant to prescribed antibiotics, yet in patients with skin or soft-tissue infections, treatment with inappropriate antimicrobials (usually B-lactam antibiotics) did not appear to correlate with differences in outcome (N.
PRIOR CATEGORY (add 000) SHARE YEAR TOTAL GENERICS $17,111,306 100% + 6% Codeine and combinations 874,089 5.1% +59% ACE inhibitors 790,580 4.6% +24% B-Lactam, increased activ.
This includes patients treated with a b-lactam drug during the prior 30 days, those who are immunosuppressed, and patients admitted to the intensive care unit.
tests for the determination of antibiotics (fo sensor) tetracycline, chloramphenicol levomycetin, streptomycin, b-lactam. 15 pack.
Notable is the production of enzymes (beta [b]-lactamases) that cleave the b-lactam ring in the whole range of b-lactam antibiotics.
In particular, cephalosporin and carbapenem use correlates highly to subsequent infection with b-lactam and/or carbapenem resistant Acinetobacter spp as a consequence of collateral damage in various studies.12-15 Hence, the use of one antimicrobial agent can enhance resistance mechanisms of the organism to other antimicrobial agents.