This kind of drug resistance is common in bacteria, which is dependent on
b-lactam antibiotics rather than [beta]-lactamases (27).
The current study was planned to observe the AmpC b-lactamases which limits the therapeutic options for infections caused by gram-negative organisms and are usually resistant to all the
b-lactam antibiotics.
In conclusion, the drug resistance is directly related to the clinical use time and range of
b-lactam antibiotics.
This is a big problem in studying
b-lactam resistance, as
b-lactam resistance can increase due to inappropriate
b-lactam use.
All cephelosporins and other
b-lactam antibiotics were highly resistant (83-100%), except piperacillin/tazobactam with 42.6% resistance.
According to them,
b-lactam resistance is widespread among Coliform bacteria due to vertical as well as horizontally acquired resistance factors.
In approximately 73% of the patients, the infecting strain of MRSA was resistant to prescribed antibiotics, yet in patients with skin or soft-tissue infections, treatment with inappropriate antimicrobials (usually
B-lactam antibiotics) did not appear to correlate with differences in outcome (N.
PRIOR CATEGORY (add 000) SHARE YEAR TOTAL GENERICS $17,111,306 100% + 6% Codeine and combinations 874,089 5.1% +59% ACE inhibitors 790,580 4.6% +24%
B-Lactam, increased activ.
This includes patients treated with a
b-lactam drug during the prior 30 days, those who are immunosuppressed, and patients admitted to the intensive care unit.
Notable is the production of enzymes (beta [b]-lactamases) that cleave the
b-lactam ring in the whole range of
b-lactam antibiotics.
In particular, cephalosporin and carbapenem use correlates highly to subsequent infection with
b-lactam and/or carbapenem resistant Acinetobacter spp as a consequence of collateral damage in various studies.12-15 Hence, the use of one antimicrobial agent can enhance resistance mechanisms of the organism to other antimicrobial agents.