In Southern Asia, the prevalence of b thalassemia has been reported to be from as low as 2% to as high as 28% in various studies5,6.
The current study was designed for assessment of serum calcium and phosphorus among transfusion-dependent b thalassemia major patients in our set up where delay in starting chelation therapy and non-compliance is common.
Metabolic and endocrinologic complications in b thalassemia major: a multicenter study in Tehran.
Hypocalcemia due to hypoparathyroidism in b thalassemia major patients.
Hypoparathyroidism in adult patients with b thalassemia Major.
Hypoparathyroidism in transfusion-dependent patients with b thalassemia. J Bone Miner Metab 2006; 24:138-45.
Bone histomorphometry in children and adolescents with b thalassemia disease: Iron-associated focal osteomalacia.
Laboratory tests were performed for diagnosis of b thalassemia include CBC, Hb electrophoresis and mutational screening.
Table-I: b Globin genotype and b thalassemia frequencies in Pakistani b-thalassemia patients.
Table-II: a Globin genotype and a thalassemia frequency of a thalassemia deletion frequencies in b thalassemia major patient.
also reported higher prevalence rate of a thalassemia carrier (8.53%), b thalassemia (2.54%) and both a and b thalassemia (0.26%) in the Guangdong Province of China.