Azurophilic granule | definition of azurophilic granule by Medical dictionary
Also found in: Dictionary
azurophilic granule A large, coarse, blue-purple membrane-bound organelle in progranulocytes, myelocytes and neutrophils, which acts as a reservoir for digestive and hydrolytic enzymes before delivery to a phagosome.
A small red or reddish-purple granule that easily takes a stain with azure dyes. Found in lymphocytes and monocytes, it is inconstant in number, being present in about 30% of the cells.
References in periodicals archive
In eliptical thrombocytes, the cytoplasma presented itself hyaline of a vacuoloid aspect especially in the poles, sometimes showing in one of the poles one of two azurophilic granules
clearly visible in most of the thrombocytes.
7) Fine or coarse azurophilic granules
are often seen in the slightly pale or basophilic cytoplasm.
The myeloid blasts in t(8; 21) AML are large, with abundant basophilic cytoplasm, with perinuclear hofs, occasional to numerous azurophilic granules
, and blunted Auer rods.
Blasts with coarse azurophilic granules
are seen in granular ALL and myeloid leukemia with basophilic differentiation, i.