Currently, there is no known medical or surgical treatment for idiopathic azoospermia
. Men with azoospermia
due to spermatogenic failure can only have children with the help of surgical methods and assisted re-productive techniques.
Theoretically, the treatment of hormonally active tumors, which may be inhibiting HPG function and thereby causing oligospermia or azoospermia
, could restore testicular function and improve fertility (Kenney et al., 2012; Schilsky, 1989).
It is less likely to work for men with the more severe form of the condition; non-obstructive azoospermia
, in which little or no sperm is produced.
Patients with ring Y chromosome can present a wide spectrum of sex phenotypes, including Turner syndrome, ambiguous genitalia, short stature, infertility because of azoospermia
, oligospermia and high gonadotropins.
While we do not recommend treating infertile men with oral testosterone undecanoate, these studies do indicate that it is highly unlikely that the short course of oral testosterone used by this man lead to prolonged azoospermia
The 2R/2R genotype has the highest frequency in total infertile, azoospermic, severe oligozoospermic, and control groups (38.78, 28.65, and 26.45 versus 31.57 percent, resp.), in which differences between total and azoospermia
patients compared to controls were statistically significant (p = 0.014, p = 0.011, resp.).
In many azoospermic men, particularly men with obstructive azoospermia
(OA), testicular sperm retrieval is performed as a randomly located open biopsy using a scalpel [1, 2]; testicular sperm aspiration (TESA) using a needle, gauge 19-26 [3, 4]; or testicular sperm extraction (TESE) using a TruCut "gun" needle, gauge 14 or 18 [5, 6].
and maturation arrest: malfunction of valves in erect poster of humans leads to hypoxia in sperm production site.
reported on the successful sperm extraction from men with non-obstructive azoospermia
and the application of intracytoplasmatic sperm injection (ICSI) method .
The complete removal of this region deletes all DAZ (deleted in azoospermia
) gene copies and 21 other transcription units.
A similar technique is given to a male partner who is diagnosed with obstructive azoospermia
, or blockage in sperm production.
: Differential diagnosis of azoospermia
is based on physical examination of the male, testicular biopsy, endocrine evaluation and genetic screening.