azidothymidine


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Related to azidothymidine: nevirapine

zi·do·vu·dine

(zī-dō'vū-dēn),
A thymidine analog that is an inhibitor of in vitro replication of HIV virus, the causative agent of AIDS and ARC, and is used in the management of these diseases.
Synonym(s): azidothymidine

azidothymidine

(ə-zī′dō-thī′mĭ-dēn′, ə-zē′-, ăz′ĭ-)
n.
See AZT.

zi·do·vu·dine

(ZDV) (zī-dō'vyū-dēn)
A thymidine analogue that is an inhibitor of in vitro replication of HIV virus; also used in pharmacotherapeutic management of AIDS.

zi·do·vu·dine

(ZDV) (zī-dō'vyū-dēn)
A thymidine analogue that is an inhibitor of in vitro replication of HIV virus; also used in pharmacotherapeutic management of AIDS.
References in periodicals archive ?
Santos et al., "Mitochondria as the target for mildronate's protective effects in azidothymidine (AZT)-induced toxicity of isolated rat liver mitochondria," Cell Biochemistry and Function, vol.
More recently, NIH-supported research played a central role in the development of AZT (azidothymidine) as an AIDS drug, and Taxol, one of the leading cancer drugs.
I don't want to go through that ordeal." Dohse, who tested positive in 1987 when he was dancing in Washington, D.C., was put on azidothymidine, or AZT, in 1990.
Understanding these mutations is critical because some can cause resistance to antibiotics such as azidothymidine (AZT).
The experimental choice of template radically influences both the measured kinetic performance of the enzyme and its response to specific inhibitors, such as azidothymidine (AZT) (9).
Interim results from the study, sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), demonstrate that a single oral dose of the antiretroviral drug nevirapine (NVP) given to an HIV-infected female in labor and another to her baby within 3 days of birth reduces the transmission rate by one-half compared with a similar short course of Azidothymidine (AZT).
* Zidovudine (Azidothymidine, AZT, Retrovir, ZDV), Glaxo Wellcome
Epstein's account centers on azidothymidine (AZT), which in September 1986 was declared by a top U.S.
Zidovudine (Retrovir or azidothymidine [AZT]) was approved in March 1987 as the first antiviral therapy for HIV disease, when a clinical thai of ZDV versus placebo in patients with advanced disease was terminated early based on evidence of improved survival (Fischl, Richman, Grieco, et al.
(10.)Commonly such treatment strategies entail decisions about antiviral drugs (either azidothymidine, AZT--also referred to as zidovudine, ZDV, or the brand-name Retrovir--dideoxyinosine (ddI), and dideoxycytidine (ddC), PCP prophylaxis (Bactrim or Intron A), and other important secondary prevention strategies such as TB screening.
For first-aid responders, this may include the HBV vaccination, gamma globulin injection, and azidothymidine (AZT) prophylaxis.