axotomy

Also found in: Wikipedia.

ax·ot·o·my

(ak-sot'ō-mē),

Incision or transection of an axon.

[axo- + G. tomē, to cut]

axotomy

Axonal damage by transection.

References in periodicals archive ?

Axotomy of Peripheral Nerve Injury (PNI), caused by trauma and medical disorders (Grinsell & Keating, 2014).

Impairment Induction by Axotomy in Motor Functional and Histological Anterior Horn of Spinal Cord Structure/Induccion del Deterioro por Axotomia en la Estructura Motora Funcional e Histologica del Asta Anterior de la Medula Espinal

In the present study, we examined the effects of topical and systemic administrations of both corticosteroids and melatonin on nerve regeneration in an FN axotomy and neurorrhaphy model.

Effects of Melatonin and Dexamethasone on Facial Nerve Neurorrhaphy

The expression of MYNN was found to be abnormal during nerve crush or axotomy in extrasynaptic myonuclei, which proved that MYNN is a likely candidate to mediate electrical activity-dependent expression of downstream synapse-specific genes [14].

Novel splice isoforms of pig myoneurin and their diverse mRNA expression patterns

(86) observed a change in the expression of three miRNAs, miRs 1,16, and 206, in different pain conditions such as peripheral inflammation, nerve ligation, or axotomy. Other studies have employed low-density TaqMan arrays to profile the expression pattern of miRNAs after spinal nerve ligation in rats and found 63 altered miRNAs (87).

Role of non-coding RNAs in non-aging-related neurological disorders

[37], on the neuromuscular synapse reaction in various conditions on WldS mice concluded that intensive stimulation in vivo resulted complete nerve blockage in vivo and intensive stimulation ex vivo all reduced synaptic protection mediated by WldSgene expression, providing direct evidence that the rate of neuromuscular synaptic degeneration in response to axotomy is, in fact, sensitive to activity and that either complete disuse or sustained high-frequency stimulation can both cause motor nerve terminals more become vulnerable to potent triggers of degeneration.

Mechanism of Synaptic Dysfunction and How This Disruption in IGF-1 homeostasis Leads to Neurodegenerative Diseases: A Theory

Macrophages infiltrate the dorsal root ganglia (DRG) and the sciatic nerve (SN) distal to the site of injury after peripheral nerve axotomy. Injury induced expression of the chemokine CCL2 in the DRG and SN attracts the macrophages to those sites.

Pre-college Poster Sessions 9:00 - 10:00 AM and 1:30 - 3:00 PM Lenhart Grand Ballroom - BTSU 202

Porreca, "Lesion of the rostral anterior cingulate cortex eliminates the aversiveness of spontaneous neuropathic pain following partial or complete axotomy," Pain, vol.

Emotional and Motivational Pain Processing: Current State of Knowledge and Perspectives in Translational Research

Blanco, "Fibroblast growth factor 2 applied to the optic nerve after axotomy increases Bcl-2 and decreases Bax in ganglion cells by activating the extracellular signal-regulated kinase signaling pathway," Journal of Neurochemistry, vol.

Effects of Transplanted Heparin-Poloxamer Hydrogel Combining Dental Pulp Stem Cells and bFGF on Spinal Cord Injury Repair

In line with this notion is the finding of similar changes in the rat facial nucleus 1 week after axotomy [9].

Botulinum Neurotoxin Application to the Severed Femoral Nerve Modulates Spinal Synaptic Responses to Axotomy and Enhances Motor Recovery in Rats

Dreesen, "Effect of local application of transforming growth factor-at the nerve repair site following chronic axotomy and denervation on the expression of regeneration-associated genes," Journal of Neurosurgery, vol.

Combined Rosiglitazone and Forskolin Have Neuroprotective Effects in SD Rats after Spinal Cord Injury

Hikawa et al., "Oxidized galectin-1 stimulates macrophages to promote axonal regeneration in peripheral nerves after axotomy," The Journal of Neuroscience, vol.

Beneficial or Harmful Role of Macrophages in Guillain-Barr Syndrome and Experimental Autoimmune Neuritis

Transplantation of embryonic stem cells improves nerve repair and functional recovery after severe sciatic nerve axotomy in rats.