axonotmesis


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axonotmesis

 [ak″son-ot-me´sis]
nerve injury characterized by disruption of the axon and myelin sheath but with preservation of the connective tissue fragments, resulting in degeneration of the axon distal to the injury site; regeneration of the axon is spontaneous and of good quality.

ax·on·ot·me·sis

(ak'son-ot-mē'sis),
Interruption of the axons of a nerve that results in degeneration of its distal (peripheral) segment (wallerian degeneration) without appreciable damage to the supporting structures (endoneurium; perineurium; epineurium) of the nerve at the site of the injury.
See also: neurapraxia, neurotmesis.
[axon + G. tmēsis, a cutting]

axonotmesis

Disruption and damage to axons and the myelin sheath with Wallerian degeneration, without disruption of schwann cells, the endoneurium, perineurium or epineurium, which is caused by greater and more prolonged mechanical trauma, and a longer and more profound neurosensory deficit than that seen in neuropraxia.

ax·on·ot·me·sis

(ak'son-ot-mē'sis)
Interruption of the axons of a nerve followed by complete degeneration of the peripheral segment, without severance of the supporting structure of the nerve; such a lesion may result from pinching, crushing, or prolonged pressure.
See also: neurapraxia, neurotmesis
[axon + G. tmēsis, a cutting]

axonotmesis

A severe injury to a peripheral nerve without severance of the sheath, so that, although the nerve fibres may have degenerated, regeneration and ultimate recovery of function is possible. Regeneration, if it occurs, does so at a rate of somewhat less than 1 mm per day.
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References in periodicals archive ?
Keywords: Axonotmesis, Electrodiagnosis, Electromyography, Neurotmesis, Radial nerve lesions.
Crush injury and transection can be considered as axonotmesis and neurotmesis, respectively [5, 29].
Immediate versus later exercises for rat sciatic nerve regeneration after axonotmesis: histomorphometric and functional analyses.
These signs indicated partial but severe right brachial plexopathy at the postganglionic level, associated with total axonotmesis of the right axillary nerve.
The severity of NBPP is classified via the Sunderland classification (I: neuropraxia, stretch; II: axonotmesis, disruption to axon and myelin; and III: neurotmesis, partial or complete disruption to the entire nerve fiber) (Seddon, 1942; Sunderland, 1951).
Although the injuries are often in neuropraxic type, they may also be due to axonotmesis. Neuropraxic injuries are mild and may result from ischaemia or mechanical compression of the nerves and usually resolve within 3 months.
This observation is because of the reason that traumatic injury patients succumb to neurotmesis which is more disabling than axonotmesis. Kretschmer et al [10] mentioned the role of occupational retraining for patients with considerable disability.
(2013) 1 injury of axillary nerve (axonotmesis) 1 fxation failure 1 plate impingement 1 superfcial wound infection Sohn et al.
In an attempt to classify the physical and functional state of the damaged nerve trunk, these injuries have also been classified into three broad categories by Seddon (5): neurapraxia, axonotmesis, and neurotmesis [Table 2].
Las lesiones postganglionares pueden ser: con preservacion del epineuro (axonotmesis) formando 1 solo neuroma o ruptura completa (neuronotmesis) formando 2 neuromas.
This "N" subtype is used for any neurological deficit, such as neuropraxia, neurotmesis, and axonotmesis.