a disorder disrupting the normal functioning of the axons.
A disorder affecting primarily the axons of peripheral nerve fibers (although secondary demyelination occurs), in contrast to one affecting only myelin (myelinopathy).
axonopathy/axo·nop·a·thy/ (ak″sah-nop´ah-the) a disorder disrupting the normal functioning of the axons; in distal a. the disease progresses from the center toward the periphery and in proximal a. the disease progresses from the periphery toward the center.
a disease of axons.
Boxer progressive axonopathy
an inherited, degenerative disorder of the peripheral and central nervous system in Boxer dogs. By 6 months of age, dogs homozygous for the trait show ataxia and weakness in the hindlimbs and an absence of the patellar reflex.
Holstein-Friesian calves are recumbent from birth; the necropsy lesion is degeneration in spinal cord and midbrain nerve tracts; considered to be inherited as an autosomal recessive trait.
inherited ovine degenerative axonopathy
inherited in several forms in some sheep breeds (Suffolk, Merino, Coopworth); may be congenital or develop at up to 6 months old; signs include ataxia, recumbency, invariable death. Probably the same disease as that called Murrurrundi disease.
peripheral and central distal axonopathy of Birman cats
see distal polyneuropathy of Birman cats.
axonopathy affecting a segment of the axons.