axonopathy

axonopathy

 [ak″sŏ-nop´ah-the]
a disorder disrupting the normal functioning of the axons.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

ax·o·nop·a·thy

(aks'on-op'a-thē),
A disorder affecting primarily the axons of peripheral nerve fibers (although secondary demyelination occurs), in contrast to one affecting only myelin (myelinopathy).
Farlex Partner Medical Dictionary © Farlex 2012
References in periodicals archive ?
In this study sample, at an assigned specificity of 90%, the sensitivity of the vibrotactile threshold for identifying distal axonopathy was 86% (Gerr et al.
Amyotrophic lateral sclerosis is a distal axonopathy: Evidence in mice and man.
ENMG results were recorded as acute inflammatory demyelinating polyneuropathy (AIDP), acute motor axonal neuropathy (AMAN), acute motor-sensory axonal neuropathy (AMSAN), or "unclassified" using specific criteria for demyelination and axonopathy (8).
Tyl and Friedman (28) elucidated this abnormality and stated that AA binds motor proteins kinesin and dynein, thereby halting transaxonal transport and leading to distal axonopathy.
(2004) Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man.
The Cell and Molecular Biology of Glaucoma: Axonopathy and the Brain.
Nerve biopsy in HSAN shows axonopathy with loss of myelinated and unmyelinated nerve fibers of all diameters but with normal appearance of brain and spinal cord [2].
On EMG, there was no sensory function abnormality, but motor axonopathy concerning for underlying neuromuscular disorder was detected.
Fernyhough, "Development of selective axonopathy in adult sensory neurons isolated from diabetic rats: role of glucose-induced oxidative stress," Diabetes, vol.
Hensley, "Semaphorin 3A signaling through neuropilin-1 is an early trigger for distal axonopathy in the SOD1G93A mouse model of amyotrophic lateral sclerosis," Journal of Neuropathology & Experimental Neurology, vol.
Pleasure, "Initiation and progression of axonopathy in experimental autoimmune encephalomyelitis," The Journal of Neuroscience, vol.