Tau phosphorylation affects its axonal transport
Hollenbeck, "The axonal transport
of mitochondria," Journal of Cell Science, vol.
In this context, one of the most studied genes is paraplegin (SPG7), a mitochondrial metalloprotease belonging to the family of ATPases associated with diverse cellular activities (AAA) [96, 97], whose mutations result in mitochondrial dysfunction of muscle tissue and mitochondrial-dependent impairment of axonal transport
Retrograde axonal transport
of BDNF in retinal ganglion cells is blocked by acute IOP elevation in rats.
We wondered whether this striking rescue might be caused, at least in part, by improvements in axonal transport
," explained Dr.
of mitochondria to synapses depends on Milton, a novel Drosophila protein.
Uptake and retrograde axonal transport
of various exogenous macromolecules in normal and crushed hypoglossal nerves.
The results demonstrate that the axonal transport
of cargo proteins is impaired in preclinical models of ALS and Parkinson's disease and correlates with disease severity.
INTRODUCTION: Location of motor neuron somata supplying forelimb muscles have been studied by retrograde cell degeneration technique ,,,, and  by electrophysiological method  and by retrograde axonal transport
of horse radish peroxidase (HRP) ,,, and  These studies have shown the locations of motor neuron somata of major forelimb nerves in cervical enlargement of spinal cord.
The central importance of protein synthesis and axonal transport
during Aplysia long-term synaptic facilitation is examined by Guan and Clark.
12) evaluation of retrograde axonal transport
of toxins to the spinal motor neurons and their response (access and possible uptake of toxic substances at the neuromuscular junction).
KineMed's techniques have also been applied to investigate other pathways such as microtubule dynamics, mitochondrial turnover and axonal transport
which are involved in HD and other neurodegenerative diseases.