Tau phosphorylation affects its axonal transport
Because HDAC6 is involved in cytoskeletal formation, modulation of cellular oxidation/reduction state, and the ubiquitin-proteasome system, inhibition of HDAC6 improves pathological conditions in neurons such as impairments in axonal transport
, oxidative stress, and protein aggresome formation in vitro [18, 19].
Mechanisms of the inhibition of fast axonal transport
by local anesthetics.
Therefore, it stands to reason that the integrity of the microtubule transport system is crucial for axonal transport
Charcot-Marie-Tooth disease neurofilament mutations disrupt neurofilament assembly and axonal transport
Small quantities of botulinum toxin can undergo retrograde axonal transport
to the central nervous system, but there is no evidence that this has any effect on humans.
* Retrograde axonal transport
of glial cell line-derived neurotrophic factor in the adult nigrostriatal system suggests a trophic role in the adult.
Subcellular structure, axonal transport
mechanisms and the structural basis of electrical and chemical signalling are described concisely.
showed that axonal transport
and presynaptic release of TDP-43 could potentially be a route of transmitting TDP-43 to the postsynaptic cells .
The transport of the administered drug into extradural or subarachnoid space either by diffusion or by the centripetal axonal transport
results in central action.