Electrophysiological tests were found to be abnormal and suggested a chronic, asymmetrical, sensory-motor axonal polyneuropathy
with possible secondary demyelination.
Electromyography (EMG) showed acute motor axonal polyneuropathy
in 2 patients, acute inflammatory demyelinating polyneuropathy in 1 patient, and entrapment neuropathy of the peroneal branch of left sciatic nerve at the level of the fibular head in 2 patients (Table 1).
Five days after admission, electromyoneurography revealed sensory motor axonal polyneuropathy
and electrophysiological studies revealed an absence of H reflex.
In axonal polyneuropathy
, there is a loss of motor units, which leads to simplification of EMG curves.
Neurophysiological findings were normal or mildly abnormal in the early stages but later on sensory axonal polyneuropathy
mainly involving the lower extremities developed.
These cases highlight the possibility of considering pathogenic variants in the GARS gene as a potential cause of early onset axonal polyneuropathy
Mazzali-Verst, "Acute axonal polyneuropathy
with predominant proximal involvement: an uncommon neurological complication of bariatric surgery," Arquivos de Neuro-Psiquiatria, vol.
The results of electrophysiological studies were compatible with motor axonal polyneuropathy
. The patient was admitted to the neurological rehabilitation program and was able to ambulate using a pair of plastic ankle-foot orthosis and walker.
She was also complaining of "shaking chills." Nerve conduction assessment revealed axonal polyneuropathy
. She was initially treated with amitriptyline and gabapentin with no improvement, and her symptoms continued to progress.
The most common neurological abnormalities encountered among the study population were sensory axonal polyneuropathy
However she developed acute axonal polyneuropathy
after cyclosporine treatment.
Electrophysiology studies showed axonal polyneuropathy
and cerebrospinal fluid (CSF) analysis was usually a cellular with normal protein levels.