axon reflex


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ax·on re·flex

a response elicited by peripheral nerve stimulation; attributed to impulses traveling proximally from the stimulation site along motor axons, encountering a branch point, and then passing distally down the other branch to activate local arterioles (to cause vasodilation) or muscle (to cause contractions). Latency of the response decreases with more proximal stimulation; axon reflex is eliminated by axon degeneration or strong stimuli but not by proximal anesthetic blocks of the nerve.

axon reflex

A localised response executed by a bifucated axon, where activation of one limb of the axon causes excitation of its collateral, resulting in the release of neurotransmitters—e.g., calcitonin gene-related peptide, and substance P—producing effects on innervated cells.
 
Axon reflex effects
Submucosal vasodilation, duodenal secretion of bicarbonates, mast-cell degranulation.