avidity


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avidity

 [ah-vid´ĭ-te]
1. eagerness, or a strong attraction for something.
2. in immunology, an imprecise measure of the strength of antigen-antibody binding based on the rate at which the complex is formed.

a·vid·i·ty

(ă-vid'ĭ-tē),
The binding strength of an antibody for an antigen.
[L. avidus, greedy, eager fr. aveo, to crave]

avidity

(ə-vĭd′ĭ-tē)
n. pl. avidi·ties

avidity

The degree of stability of an antibody’s binding with its antigen, which is a function of the number of shared binding sites and the binding energy of the antibody and antigen, which is the sum of the binding affinities of the combining sites on the antibody.

avidity

Immunology The degree of stability of an antibody's binding with its antigen, which is a function of the number of shared binding sites and the binding energy of an antibody and antigen–the sum of the binding affinities of the combining sites on the antibody. Cf Affinity.

a·vid·i·ty

(ă-vid'i-tē)
A measure of the binding strength of a multivalent antibody to a multivalent antigen.
See also: affinity
[L. avidus, greedy, eager fr. aveo, to crave]
References in periodicals archive ?
Accordingly, the low avidity rate was 4.66% (95% CI: 0.969 to 10.906) and the Cochrane Q test was 10,3230; [I.sup.2]=70.94% (p<0.0001) in 427 pregnant in four studies(10-13), intermediate avidity rate was 7.51% (95% CI: 5.101 to 10.345), and the Cochrane Q test was 1,8145; [I.sup.2]=0.00 (p=0.404) in 384 pregnant in three studies(11-13), the high avidity rate was 93.55% (95% CI: 82.584 to 99.311), and the Cochrane Q test was 46,4845, [I.sup.2]=91.39% (p<0.0001) in 522 pregnant women in five studies(3,10-13).
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Specifically, we sought to show that emergence of substitutions at HA1 position 180 are driving increases in virus receptor-binding avidity, including for human-like receptor analogs, and concurrently enabling virus to escape antibody-based immunity (Appendix, https://wwwnc.cdc.gov/ EID/article/25/1/18-0616-App1.pdf).
Avidity Science is a worldwide leader in water purification systems and laboratory equipment for scientific research and healthcare facilities.
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In addition, information concerning curettage, amniotic biopsy or malformation in patients with IgM seropositivity and moderate and low avidity was not available.
IgG Avidity. In this study, we also detected the dynamic changes of IgG avidities to PPD, ESAT-6, CFP10-ESAT-6, and Ag85b (Figure 7).
Blood sample collection was performed before treatment and after treatment for the analysis of immunoglobulin levels and avidity. The research protocol was approved by the Institutional Review Boards of Osaka City University Graduate School of Medicine, Osaka, Japan, and Fukujuji Hospital, Tokyo, Japan, and by the Research Ethics Committee of the National Institute of Infectious Disease, Tokyo, Japan.
For determination of IgG avidity commercial ELISA using urea as a denaturing factor was carried out as described by the manufacturer.
Second, the higher avidity of IgG allows the preferential binding of TF-positive ligands despite the possible interference of the other Ig isotypes.
Of the cytomegalovirus immunoglobulinM-positive women, sera of 40(80%) had immunoglobulinG avidity >50%.
SuperCom (NASDAQ: SPCB) subsidiary Alvarion has released Avidity series of indoor and outdoor access points based on the latest 802.11ac standard, the company said.