avidin


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av·i·din

(av'i-din),
A glycoprotein, obtained from egg whites, that possesses a high affinity for biotin. Labeled avidin is allowed to bind to biotin-tagged antibodies to amplify antigen-antibody reactions that may be difficult to visualize. Ingestion of avidin can cause a biotin deficiency.
Synonym(s): antibiotin
[L. avidus, eager fr. aveo, to crave + -in]

avidin

(ăv′ĭ-dĭn)
n.
A protein found in uncooked egg white that binds to and inactivates biotin.

avidin

a glycoprotein in raw egg white that interacts with biotin to make it unavailable to the body. Cooking destroys avidin.

avidin

A 68-kD tetrameric glycoprotein found in egg white which has a high affinity for biotin, an association used in immunology for the avidin-biotinylated immunoperoxidase method. When eggs are eaten in excess, avidin-biotin avidity may cause biotin deficiency.

av·i·din

(av'i-din)
Glycoprotein obtained from egg whites that possesses a high affinity for biotin; ingestion can cause biotin deficiency.
[L. avidus, eager fr. aveo, to crave + -in]

avidin (av´idin),

n a glycoprotein in nondenatured egg whites (raw) that binds biotin and prevents its absorption, causing biotin depletion.

avidin

a constituent of normal eggs which inhibits the absorption of biotin. The feeding of large quantities of raw egg whites causes dermatitis, alopecia and cracked hooves in pigs and heavy mortality in mink.
References in periodicals archive ?
Positions of conjugated avidin groups depicted in the diagram are arbitrarily chosen.
After adding avidin to the modified S1-ADP-Vi, the complex of actin-tropomyosin and S1-ADP-Vi, of which the biotinylated ADP was associated tightly with avidin, was observed by electron microscopy.
In the second method, an unlabeled avidin film and a ds-DNA film were assembled on the semiconductor electrode.
The activity of acetyl-CoA carboxylase in mammary gland nuclei-free homogenates prepared in the presence and absence of avidin indicates that polymerization/ depolymerization are not solely responsible for the modification of activity (Table 4).
Naturally-occurring avidin usually collects undesired fats and damaged cells and membranes from the blood, taking them to the white blood cells and releasing them for destruction as part of the body's natural 'clean-up' system.
Avidin was introduced into plants by particle gun bombardment, and commercially economic levels of expression were obtained under the control of a constitutive promoter (Hood et al.
The avidin-biotin complex is resistant to proteolytic digestion in the gastrointestinal tract however avidin is heat labile and therefore ingestion of cooked eggs does not compromise biotin absorption (2).
Then, they added orange-emitting quantum dots that they had previously linked to avidin, a molecule that readily binds to these antibodies.
The second designer polymer, poly-2c contains a biotin group which changes colour when exposed to Avidin, a protein known to bind to biotin (Figure 2).
Three of their products, avidin, beta-glucuronidase and aprotinin (a protease inhibitor commonly used by surgeons), have been produced in sufficient quantities to be sold through a commercial chemical supplier, the St.
The very strong affinity between biotin (a vitamin) and avidin (a protein) ensures that the CD34+ cells stick to the beads and that, subsequently, the entire avidin-biotin-antibody complex can be detached from the cells by mechanical agitation.
PARIS -- Endotis Pharma, a world leader in the development of neutralizable anticoagulants, today announced enrolment of the first patients into a Phase IIa study using EP217609 and its specific antidote avidin to manage coagulation during open-heart surgery.