AVERT

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AVERT

Cardiology Atorvastatin VErsus Revascularization Treatments. A trial comparing the efficacy of aggressive lowering of cholesterol in patients at risk of future cardiovascular events (ischaemic heart disease and stable angina) to percutaneous coronary intervention.
Conclusion Atorvastatin evoked a 46% reduction in LDL-C compared to an 18% reduction with revascularization; ischaemic events were 36% lower with atorvastatin than with revascularisation; the first ischaemic event occurred after a much longer time in atorvastatin patients. Aggressive LDL-C lowering in patients with stable CAD results in a markedly reduced risk of cardiovascular events (nonfatal heart attack, bypass surgery, revascularization, and worsening angina) compared with patients receiving angioplasty followed by usual care. In AVERT, 13% of patients treated with atorvastatin suffered a cardiovascular event compared with 21% of patients receiving angioplasty and usual care.
Cardiovascular surgery Artificial Valve Endocarditis Reduction Trial. A trial comparing the St. Jude masters series valve with silver (Silzone) coated sewing cuff with the St Judes mechanical heart valve with uncoated cuff
Logistics Randomised, multicenter.
Conclusion Trial was stopped in 2000, when 807 patients had been randomised, because of an increased risk of major paravalvular leak leading to valve explant in the Silzone arm of the study.

AVERT

Cardiology
1. A clinical trial—Atorvastatin Versus Revascularization Treatments–which evaluated the efficacy of aggressive lowering of cholesterol in Pts at risk of future cardiovascular events.
2. A clinical trial–Artificial Valve Endocarditis Reduction Trial.
References in periodicals archive ?
The proportion of potential maternal deaths averted by contraceptive use varied widely by individual country, ranging from 7% in Chad to 61% in most developed countries and many developing countries, including Brazil, China, Iran, Mauritius, Russia and Thailand.
An airline official and state media reported that the pilot's actions had averted "a major disaster".
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More information about the decision-making of government might have averted an estimated Jam$10 billion of damage and the loss of life.
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Next month we kick off our Membership Campaign, and a quick review of what we have accomplished since January amply illustrates the benefits of BOMA/NY and the power of teamwork in building the best *32B/J Strike Averted. Just five days into the new year, a major strike by 32B/J was averted and a settlement obtained.
In 1990, a nuclear conflict between India and Pakistan over Kashmir was narrowly averted, and little has happened since to reduce the prospect of a recurrence.
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Shri Balwant averted a serious accident by noticing the collapsed ballast retainer of the bridge in Thandla- Bajranggarh station in Ratlam Division.