Similarly, one of the target transcription factors for this cytokine is the activation of NF-[kappa]B, which has been involved in the increase of NOS and IL-1[beta] autostimulation
, and it promotes PBC dysfunction [163, 168] (Figure 5).
Gerhardinger, "IL-1[beta] is upregulated in the diabetic retina and retinal vessels: cell-specific effect of high glucose and IL-1[beta] autostimulation
," PLoS One, vol.
Increased interleukin (IL)-1 b messenger ribonucleic acid expression in [beta]-cells of individuals with type 2 diabetes and regulation of IL-1 b in human islets by glucose and autostimulation
. J Clin Endocrinol Metab 93(10):4065-4074, PMID: 18664535, https://doi.org/10.1210/jc.2008-0396.
Interestingly, our experiments did not reveal any autostimulation
of leptin or its receptor.
(261) In that same passage, he holds (in perhaps 'prematurely technical' fashion) that the psychoanalytic interpretation of dreams can be dispensed with in favor of 'aminergic demodulation and cholinergic autostimulation
. [as well as] the overall connectivity of neurons ...' (261) At the very least, we can be sure that the interdisciplinary knowledge of the future will not include phenomenology, psychoanalysis, or mainstream analytic philosophy.
Dennett speculates that "the greater virtues of sotto voce" talking might have led our ancestors to entirely silent talking, "maintain[ing] the loop of self-stimulation, but jettison[ing] the peripheral vocalization and audition portions of the process, which weren't contributing that much." He notes such an innovation would preserve "a certain privacy for the practice of autostimulation
" (1991, 197).
Gerhardinger, "IL-1beta is upregulated in the diabetic retina and retinal vessels: cell-specific effect of high glucose and IL-1beta autostimulation
," PloS One, vol.
of T lymphocytes and induction of Th1 type cytokines," Journal of Clinical Investigation, vol.