autologous transplant


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Related to autologous transplant: allogeneic transplant, syngeneic transplant

autologous transplant

A generic term for the administration of tissues or cells, in particular bone marrow, which had been removed before high-dose chemo- and/or radiotherapy.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
Patients without a donor were randomized to either consolidation/maintenance chemotherapy for 2.5 years or a single autologous transplant. Prior to treatment, all patients received three courses of high-dose methotrexate as intensification therapy.
What are the odds of the child needing an autologous transplant, how would one determine these odds, and would there be guarantee of viable cells?
Holding back tears she said: "The autologous transplant will only prolong Wesley's life a little more than six months.
Patients in the study were given induction chemotherapy followed by autologous transplant.
After a median follow-up of 4 years, relapses were most frequent in the cytarabine group (61%) less common in the autologous transplant group (48%), and lowest in the allogeneic transplant group (29%).
Therefore, the use of autologous transplants or synthetic materials is required to replace the tissue.
Analysis of factors that influence hematopoitic recovery in autologous transplanted patients with hematopoietic stem cells from peripheral blood.
Autologous transplants use the patient's own blood cells, while allogenic transplants use cells from a matched donor.
For instance, it is generally accepted as a sign of engraftment failure and disease recurrence in autologous transplants (1).
The NCCCR has also processed about 36 autologous transplants so far for blood related cancer treatment, an official said Wednesday.
The finding provides a scientific basis for enhancing the effectiveness of autologous bone marrow transplants, in which the recipient donates his or her own stem cells prior to the procedure."Up to 10 percent of bone marrow donors fail to mobilize sufficient numbers of stem cells, which impedes autologous transplants and significantly delays transplant recovery time," said Hartmut Geiger, Ph.D., a researcher in the division of Experimental Hematology/Cancer Biology at Cincinnati Children's and senior investigator on the study.
However, the chemotherapy agents associated with autologous transplants can have long-lasting cardiopulmonary, immunosuppressive, renal, and other side effects that affect quality of life (Buchsel & Whedon, 1995).

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