autoimmune response


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Related to autoimmune response: Autoimmune disorders

response

 [re-spons´]
any action or change of condition evoked by a stimulus.
acute phase response a group of physiologic processes occurring soon after the onset of infection, trauma, inflammatory processes, and some malignant conditions. The most prominent change is a dramatic increase of acute phase proteins in the serum, especially C-reactive protein. Also seen are fever, increased vascular permeability, and a variety of metabolic and pathologic changes.
anamnestic response the rapid reappearance of antibody in the blood following introduction of an antigen to which the subject had previously developed a primary immune response.
auditory brainstem response ABR; a special hearing test that tracks the nerve signals arising in the inner ear as they travel along the auditory nerve to the brain region responsible for hearing. A small speaker placed near the ear makes a clicking sound, and special electrodes record the nerve signal as it travels. The test can determine where along the nerve there is a lesion responsible for sensorineural hearing loss. It is often used for individuals with such loss in just one ear; this is often caused by a benign tumor along the auditory nerve, but if the ABR reading is normal in a given region, the chances of there being a tumor there are small. This test can also be used on infants since it requires no conscious response from the person being tested.
autoimmune response the immune response in which antibodies or immune lymphoid cells are produced against the body's own tissues. See also autoimmune disease.
conditioned response see conditioned response.
dysfunctional ventilatory weaning response a nursing diagnosis adopted by the North American Nursing Diagnosis Association, defined as inability of a patient to adjust to lowered levels of mechanical ventilator support, which interrupts and prolongs the process of weaning. See also mechanical ventilatory weaning.
galvanic skin response the alteration in the electrical resistance of the skin associated with sympathetic nerve discharge.
immune response see immune response.
inflammatory response the various changes that tissue undergoes when it becomes inflamed; see inflammation.
post-trauma response former name for the nursing diagnosis post-trauma syndrome.
reticulocyte response increase in the formation of reticulocytes in response to a bone marrow stimulus.
triple response (of Lewis) a physiologic reaction of the skin to stroking with a blunt instrument: first a red line develops at the site of stroking, owing to the release of histamine or a histamine-like substance, then a flare develops around the red line, and lastly a wheal is formed as a result of local edema.
unconditioned response an unlearned response, i.e., one that occurs naturally, in contrast to a conditioned response.

autoimmune response

A generic and nonspecific term for any response of a host’s immune system to self-tissues, cells, or molecules.
References in periodicals archive ?
Recently, higher circulating levels of IP-10, IFN-[gamma] and IL-18 were reported in patients with T1D, LADA, and FDRs positive for islet autoantibodies [27, 36-40], suggesting that IP10 level might represent clinical marker of Th1 autoimmune response. These data implicate proinflammatory changes in cellular immunity in prediabetics which is in line with our observations.
In addition to the above mechanisms of actions (as shown in Figures 3 and 4), these autoimmune responses and diseases can be induced by solvents and other environmental chemicals through a variety of effects at the biochemical and cellular levels.
In an autoimmune response, the antibody binds to a myelin protein; this causes the immune system to attack the myelin.
Current evidence suggests that hair follicle inflammation in AA is caused by T cell- mediated autoimmune response in genetically predisposed persons.1 There is an increased frequency of other autoimmune diseases, both cutaneous and extracutaneous conditions.2
(44) As these cells are resistant to apoptosis they are capable of perpetuating the aberrant autoimmune response. (44) Alternative hypotheses to explain the association between EBV and other autoimmune diseases include molecular mimicry eluded to above (26,28) and that EBV operates indirectly by activating the pathogenic expression of endogenous retroviruses such as HERV-W, which has also been postulated to play an aetiological role in MS.
It's arguable that NCLB is an autoimmune response. NCLB was intended to raise education levels by holding schools responsible for student performance.
"The doctors think it was an autoimmune response, where my own immune system attacked my lungs, but they say it's idiopathic, which means it's unknown."
IA was defined as being positive in two or more measurements of autoantibodies indicative of the autoimmune response: glutamic acid decarboxylase (GADA); tyrosine phosphatase (IA-2A); insulin autoantibodies (IAA) analysed at the three time points or being diagnosed with type 1 diabetes during the 5 year follow up period.
This study is an extension of a previous study (Almogairen et al, Lupus 2009 April) 17,but examines the correlation between the autoimmune response and the histopathological changes in the thyroid gland.
The cause of multifocal choroiditis is unknown, although some studies suggest an autoimmune response to an infection.
In people with celiac disease, eating certain types of protein, called gluten, sets off an autoimmune response that causes damage to the small intestine, which in turn affects the ability of the small intestine to absorb the nutrients found in food.
Type 1 diabetes is caused by an autoimmune response which destroys insulin-producing islet cells in the pancreas.

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