autoantigen
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autoantigen
[aw″to-an´tĭ-jen]an antigen that, despite being a normal tissue constituent, is the target of a humoral or cell-mediated immune response, such as in autoimmune disease.
au·to·an·ti·gen
(aw'to-an'ti-jen),A "self" antigen; any tissue constituent that evokes an immune response by the host.
autoantigen
/au·to·an·ti·gen/ (-an´tĭ-jen) an antigen that despite being a normal tissue constituent is the target of a humoral or cell-mediated immune response, as in autoimmune disease.autoantigen
(ô′tō-ăn′tĭ-jən)n.
An endogenous antigen that stimulates autoantibody production, as in an autoimmune reaction.
autoantigen
[ô′tō·an′tijin]
Etymology: Gk, autos + anti, against, genein, to produce
an endogenous body constituent that stimulates the production of autoantibodies and an autoimmune reaction. An autoantigen associated with Addison's disease has been identified as the enzyme 17 α-hydroxylase. Also called self-antigen. See also antibody-specific model, autoantibody, autoimmune disease.
autoantigen
Any of an organism’s own antigens (self-antigens)—e.g., glomerular basement membrane, mitochondria, muscle, parietal cells, thyroglobulin and others, which may evoke production of autoantibodies.autoantigen
Immunology Any self antigen–eg, glomerular basement membrane, mitochondria, muscle, parietal cells, thyroglobulin and others, which may evoke production of autoantibodies. See Antigen.au·to·an·ti·gen
(aw'to-an'ti-jĕn)A "self" antigen; any tissue constituent that evokes an immune response by the host.
autoantigen
a tissue constituent that stimulates production of autoantibodies or self-reactive T lymphocytes in the animal in which it occurs.