autoagglutination


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autoagglutination

 [aw″to-ah-gloo″tĭ-na´shun]
1. clumping or agglutination of an individual's cells by his own serum (containing autoantibody), as in autohemagglutination. Autoagglutination occurring at low temperatures is called cold agglutination.
2. nonspecific clumping or agglutination of particulate antigens that does not involve antibody.

au·to·ag·glu·ti·na·tion

(aw'to-ă-glū'ti-nā'shŭn),
1. Nonspecific agglutination or clumping together of cells (for example, bacteria, erythrocytes) caused by physical or chemical factors.
2. The agglutination of erythrocytes by a specific autoantibody present in one's own serum.

autoagglutination

The aggregation of red blood cells in a person’s own serum, often caused by a cold-reacting antibody, as seen in cold agglutinin disease or other autoimmune haemolytic anaemias.

autoagglutination

Hematology The aggregation of RBCs, often caused by a cold-reacting antibody, as seen in cold agglutinin disease or other autoimmune hemolytic anemias.

au·to·ag·glu·ti·na·tion

(aw'to-ă-glū'ti-nā'shŭn)
1. Nonspecific agglutination or clumping together of cells (e.g., bacteria, erythrocytes) due to physical-chemical factors.
2. The agglutination of red blood cells by specific autoantibody present in one's own serum.

autoagglutination

The spontaneous clumping together of red blood cells. This is a feature of the AUTOIMMUNE DISEASE haemolytic anaemia
References in periodicals archive ?
Autoagglutination. Each strain was inoculated into two tubes of Methyl Red-Voges Proskauer broth (Merck).
In this study, virulence phenotypic tests for Y enterocolitica B1A strains produced negative results excepting autoagglutination at 37[degrees]C; however, the yadA gene was not detected by PCR.
Saline controls were included to detect autoagglutination. Biotypes were determined by PCR of specific regions of the biotyping (tcpA) gene (3).
Moreover, autoagglutination on the peripheral blood film, which disappears on warming the blood sample, suggests a cold antibody.
canis tend to aggregate even in the absence of specific antibodies, a less mucoid variant termed M-, which does not produce autoagglutination is used for serologic diagnosis (3).
The M- strain has been widely used for the diagnosis of canine brucellosis because it is less prone to autoagglutination than its wild-type counterpart (called M+).
Some colonies of the O153:H- EHEC strain isolated from the first outbreak of HUS in DB rabbits (6) and a strain of unknown O serotype that showed autoagglutination were sorbitol negative like most O157:H7 EHEC organisms isolated from humans.
One (14%) of the 7 rabbits was infected with an EHEC of unknown O serotype that showed autoagglutination (DB 02-177, isolate 03-192) and was co-infected with enteropathogenic E.
We observed four distinct patterns of adherence: LA occurred when the bacteria attached to localized areas of the HEp-2 cells in culture, forming distinct microcolonies after 3 h of incubation; DA occurred when bacteria adhered to the entire surface of the HEp-2 cells without formation of discrete microcolonies; AA was distinguished by prominent autoagglutination of the bacterial cells to each other on the surface of the cells, as well as those of glass or plastic containers; and LAL pattern, observed only in strains incubated for 6 h, was characterized by the formation of microcolonies or clusters less dense and compact than those displayed by typical LA-positive strains.