atypical vascular lesion

atypical vascular lesion

A well-circumscribed uni- or multifocal vascular proliferation that develops months to years after radiotherapy for breast cancer.
References in periodicals archive ?
Angiosarcoma, radiation-associated angiosarcoma, and atypical vascular lesion.
Clinicopathological and immunohistochemical study of 30 cases of post-radiation atypical vascular lesion of the breast.
8) Coamplification of the FMS-like tyrosine kinase 4 (FLT4) gene encoding the vascular endothelial growth factor receptor 3 (VEGFR3), in association with MYC amplification, was found by Guo et al (10) in 25% of secondary angiosarcomas but not in other radiation-associated, atypical vascular lesions.
Immunohistochemical staining and fluorescence in situ hybridization for MYC are helpful in distinguishing benign and atypical vascular lesions (AVLs) from secondary angiosarcoma because expression and amplification of MYC have been described in secondary angiosarcomas and are absent in AVLs.
Postradiation cutaneous angiosarcoma after treatment of breast carcinoma is characterized by MYC amplification in contrast to atypical vascular lesions after radiotherapy and control cases: clinicopathological, immunohistochemical and molecular analysis of 66 cases.
Consistent MYC and FLT4 gene amplification in radiation-induced angiosarcoma but not in other radiation-associated atypical vascular lesions.
Cutaneous angiosarcoma and atypical vascular lesions of the skin and breast after radiation therapy for breast carcinoma.
Radiation-Associated Angiosarcoma of the Breast
In 1994, Fineberg and Rosen3 reported 4 cases of an unusual vascular lesion occurring in mammary skin after radiation, which they named atypical vascular lesion (AVL).
Atypical vascular lesion usually presents as 1 or more small, flesh-colored papules or erythematous patches that arise in radiated skin.
Radiation-associated cutaneous atypical vascular lesions and angiosarcoma: clinicopathologic analysis of 42 cases.
Angiosarcoma, radiation-associated angiosarcoma, and atypical vascular lesion
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