atypical nevus

atypical nevus

(1) Dysplastic naevus, see there.
(2) Any naevus with atypical features, often looked for as a sign of potential malignancy.

atypical nevus

Dermatology A pigmented lesion with a clinical appearance that differs from a 'garden variety' mole, which may be larger, have irregular borders, lack uniformity of color; it can be flat or raised above the skin surface. See Nevus.
References in periodicals archive ?
In most cases, the histologic differential diagnosis was between Spitz nevus and spitzoid melanoma or between atypical nevus (such as variants of deep penetrating/clonal/inverted type-A nevus, pigmented spindle cell nevus, atypical genital nevus, atypical conjunctival nevus showing cytologic atypia, mitotic activity, limited maturation, or proliferative nodules, among others) and nevoid melanoma (Table 1).
For each major diagnostic category of histologically ambiguous lesion (spitzoid tumors, lesions raising a differential diagnosis of an atypical nevus versus nevoid melanoma, and dysplastic nevus versus superficial spreading melanoma), Table 1 shows the initial MelanoSITE results and the final FISH result interpretation after correcting for false-positive results.
None of the lesions thought to represent atypical nevus showed abnormal FISH results, whereas 48% of lesions favored to represent melanoma had abnormal FISH results.
If the FISH result is normal and the initial impression was that of a severely atypical but benign lesion, the FISH findings are interpreted as reassuring, and in most cases a biopsy is reported as consistent with an atypical nevus.
26) Benign nevi are not rare in acral locations, which was found in mole distribution studies in patients with atypical nevus syndrome.

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