(2) Well-differentiated liposarcoma (WDL), also known as atypical lipomatous tumor
, is the most common subtype.
Atypical lipomatous tumor
(ALT) and well-differentiated liposarcoma (WDL) are rare liposarcoma subtypes that are histologically identical but distinguished by the 2002 WHO classification: ALTs occur in surgically amenable locations, whereas WDLs do not.
Despite the growth pattern similarity between IML and well-differentiated liposarcoma/ atypical lipomatous tumor
, it can usually be differentiated.
Here, we report the case of a 73-year-old patient with LGMD type 2B (LGMD2B) who developed an atypical lipomatous tumor
(ALT), an intermediate or locally aggressive form of adipocytic tumor that is also referred to as well-differentiated liposarcoma (WDLS) .
Tumor type Total (n) Percentage Benign tumors Adenomatoid tumor 1 2.1 Solitary fibrous tumor 1 2.1 Lipoma 3 6.4 Hemangioma 1 2.1 Adenoma 1 2.1 Malignant tumors Mesothelioma 1 2.1 Malignant fibrous histiocytoma 1 2.1 Embryonal rhabdomyosarcoma 3 6.4 Atypical lipomatous tumor
1 2.1 Myxoid liposarcoma 1 2.1 Tumor-like lesions Fibromatous periorchitis 2 4.3 Mesothelial cyst 1 2.1 Epididymal cyst 17 36.2 Tuberculous epididymitis 7 14.9 Filarial epididymitis 4 8.5 Non-specific granulomatous 2 4.3 epididymitis Total 47 100.0 Table 2: Site distribution of paratesticular tumors.
However, it is important to differentiate a lipoma from an atypical lipomatous tumor
, which may have a similar appearance but, unlike a lipoma, can on occasion develop into a cancer (your brother should see an orthopaedic or surgical oncologist if he has any concerns).
INTRODUCTION: Dedifferentiated liposarcoma represents a malignant adipocytic neoplasm showing transition from atypical lipomatous tumor
or well-differentiated liposarcoma to nonlipogenic sarcoma of variable histologic grade, usually at least several millimeters in diameter.
Subconjunctival herniated orbital fat: a benign adipocytic lesion that may mimic pleomorphic lipoma and atypical lipomatous tumor
. Am J Surg Pathol.
p16 immunohistochemistry as an alternative marker to distinguish atypical lipomatous tumor
from deep-seated lipoma.
FNAC report primarily revealed to be an atypical lipomatous tumor
; to which initially he ignored as it was not causing too much distress; but after 3 months he felt that this tumor had been increasing very rapidly; then he consulted us in our medical institute where on examination a foul smelling giant mass in the left scapular region was found (Fig-1); which was extending from mid axillary line to vertebral column and from shoulder to 12th rib and on palpation it was non-tender and firm to hard in consistency.
One of them is atypical lipomatous tumor
or well-differentiated liposarcoma.
Evans, "Atypical lipomatous tumor
, its variants, and its combined forms: a study of 61 cases, with a minimum followup of 10 years" The American Journal of Surgical Pathology, vol.