atypical dermatofibroma

(redirected from atypical fibrous histiocytoma)

atypical dermatofibroma

A histologic variant of benign fibrous histiocytoma (BFH) which more commonly affects men. It is characterised by scattered cells with bizarre nuclear pleomorphism and large hyperchromatic nuclei.
 
DiffDx
Atypical fibroxanthoma.
References in periodicals archive ?
The differential diagnosis of AFX is focused primarily on poorly differentiated variants of SCC, melanoma, cutaneous leiomyosarcoma, and atypical fibrous histiocytoma. Metastatic tumors and angiosarcomas could be considered in some cases.
Atypical fibrous histiocytoma is the atypical variant of dermatofibroma (fibrous histiocytoma).
Atypical fibrous histiocytoma with aberrant cytokeratin-5/6 expression.
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