atypical apocrine adenosis

atypical apocrine adenosis

A rare (< 1% of cases) breast lesion that may be misdiagnosed as carcinoma, especially in a background of radial scars and atypical apocrine metaplasia. It primarily affects women who are older than other patients with benign breast disease; it is neither aggressive nor premalignant.
References in periodicals archive ?
Among atypical and malignant lesions with apocrine features are atypical apocrine adenosis (AAA), apocrine ductal carcinoma in situ (DCIS), and invasive carcinoma with apocrine features.
12 The term atypical apocrine adenosis refers to apocrine atypia within sclerosing adenosis (Figure 4).
Atypical apocrine adenosis of the breast; a clinicopathological study of 37 patients with 8.
Atypical apocrine adenosis of the breast: long term follow-up in 37 patients.
Kleer, MD, report the morphologic and diagnostic features of atypical apocrine adenosis, an uncommon yet very challenging breast lesion.
3) It is well recognized that the cytologic alterations can be misdiagnosed as apocrine ductal carcinoma in situ (apocrine DCIS) if pathologists do not apply diagnostic criteria for atypical apocrine adenosis (AAA).
The objective of this study was to determine the breast cancer risk in a retrospective series of patients diagnosed with atypical apocrine adenosis in otherwise benign breast excisional biopsies.
8) Atypical apocrine adenosis may involve sclerosing lesions, but by definition, it lacks distended epithelium-lined spaces or complex architectural features of DCIS.
Atypical apocrine adenosis of the breast: a clinicopathologic study of 37 patients with 8.
There is some evidence that atypical apocrine adenosis lesions are associated with increased breast cancer risk.
APM involving radial sclerosing lesion, adenosis or papilloma, including atypical apocrine adenosis
Microscopic examination of the left breast biopsy revealed benign proliferative changes, cysts, and multiple foci of atypical apocrine adenosis with microcalcifications.