Digital readout of target binding with attomole
detection limits via enzyme amplification in femtoliter arrays.
quantification and global profile of RNA modifications: epitranscriptome of human neural stem cells," Nucleic Acids Research, vol.
Heinecke, "Mass spectrometric quantification of 3-chlorotyrosine in human tissues with attomole
sensitivity: a sensitive and specific marker for myeloperoxidase-catalyzed chlorination at sites of inflammation," Free Radical Biology and Medicine, vol.
The Agilent 6495 Triple Quadrupole MS/MS provides targeted MRM peptide quantitation at attomole
The company's 6495 Triple Quadrupole MS/MS enables targeted MRM peptide quantitation at attomole
Feng, "S-glutathionyl quantification in the attomole
range using glutaredoxin-3-catalyzed cysteine derivatization and capillary gel electrophoresis with laser-induced fluorescence detection," Analytical and Bioanalytical Chemistry, vol.
Mann, "Absolute SILAC for accurate quantitation of proteins in complex mixtures down to the attomole
level," Journal of Proteome Research, vol.
Quantitative femtoto attomole
immunodeteetion of regulated secretory vesicle proteins critical to exocytosis, Anal.
detection of in vivo protein targets of benzene in mice: evidence for a highly reactive metabolite.
Technology is used for ultrasensitive quantification of proteins and peptides down to low attomole
The 6520 Q-TOF offers high performance in important categories, including attomole
sensitivity; better than 2-ppm MS mass accuracy; better than 5-ppm MS-MS mass accuracy; tenfold improvement in in-spectra dynamic range without loss of sensitivity; mass resolution to 20,000; fast data acquisition ([greater than or equal to] = 10 MS-MS spectra/sec) compatible with fast LC chromatography; and broad mass range from m/z 25 to 20,000.