attenuated


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Related to attenuated: Attenuated total reflectance

attenuated

[əten′yo̅o̅·ā′tid]
Etymology: L, attenuare, to make thin
pertaining to the dilution of a solution or the reduction in virulence or toxicity of a microorganism or a drug by weakening it.

attenuated

adjective Medtalk
1. Reduced in virulence or infectivity.
2. Thin, minimal, markedly reduced or decreased.

attenuated

Weakened or reduced, and so altered in characteristics so as no longer to be dangerous. The term is applied to organisms that have been specially cultured so as to reduce their virulence and make them suitable for use in vaccines.

Attenuated

Alive but weakened; an attenuated microorganism can no longer produce disease.
Mentioned in: Tuberculin Skin Test

attenuated

having undergone a process of attenuation.

attenuated breath sounds
normal breath sounds audible via a stethoscope over the lungs.
References in periodicals archive ?
Pathogenicity of attenuated IBH-HPS virus was tested in 80 broiler birds of 15 days old, reared in the Animal House of Institute of Microbiology.
Our further research illustrated that MSC infusion significantly attenuated the degree of PMN pulmonary sequestration and NE release induced by impropriate ventilation as well as inflammatory chemokines and cytokines (including TNF-a, IL-6 and MIP-2), and do not affect the IL-10s (one type of anti-inflammatory cytokine), which consisted with previous VILI research.
In a study of rhesus macaque monkeys given attenuated SIV, the simian counterpart to HIV, the vaccine killed off many of the monkeys that received it.
This notion is supported by findings that systemic immunization with attenuated macaque-specific Simian immunodeficiencv virus induced virus-specific CTL responses in gut-associated lymph nodes and limited superinfection following mucosal challenge (33).
What's more, the work "fortifies the idea that you can have an attenuated virus in an individual without causing disease.
Louis wanted to know if, in the close confines of a day care environment, the live, attenuated virus used in a chicken pox vaccine (not yet on the market) could jump from a vaccinated child to a nonvaccinated child.
In addition to standard fiber optic patch cords and attenuated test cables, Timbercon has pioneered proprietary products, many of which are now considered to be an industry benchmark.
The Company is building a pipeline of next generation cancer immunotherapies by combining its proprietary attenuated Listeria vaccine platform with promising disease antigens.
The presentation highlights the application of a technology platform for the use of attenuated autologous autoreactive T-cells for vaccinations in T-cell mediated autoimmunity.
Rotarix(R) is an oral, two-dose, live attenuated vaccine against rotavirus disease in infants that was licensed in 1997 by AVANT Immunotherapeutics to GSK for worldwide commercialization.
The anti-hyperglycemic capabilities of PSN010 have been confirmed in several diabetic rodent models and maximal glucose concentrations were significantly attenuated by the drug candidate.
Advances in the identification of people with attenuated psychotic symptoms, a group generally at increased risk for psychosis, have allowed for the development of novel intervention strategies.