attenuated


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Related to attenuated: Attenuated total reflectance

attenuated

adjective Medtalk
1. Reduced in virulence or infectivity.
2. Thin, minimal, markedly reduced or decreased.

attenuated

Weakened or reduced, and so altered in characteristics so as no longer to be dangerous. The term is applied to organisms that have been specially cultured so as to reduce their virulence and make them suitable for use in vaccines.

Attenuated

Alive but weakened; an attenuated microorganism can no longer produce disease.
Mentioned in: Tuberculin Skin Test
References in periodicals archive ?
Principles underlying the development and use of live attenuated cold-adapted influenza A and B virus vaccines.
The observed efficacy of live, attenuated vaccines for human interpandemic influenza, together with the findings to date that inactivated or subunit AI vaccines are suboptimally immunogenic in humans, strongly suggests that using live vaccines against pandemic influenza is worth exploring.
"I think this current approach to generating a live attenuated AIDS vaccine is doomed," says Ruth M.
Vaccine effectiveness was estimated to be 48% in all age groups and for each virus subtype or lineage (95% confidence interval, 41-55; P less than .001); however, significant effectiveness was observed for only the inactivated influenza vaccine (P less than .001), compared with the quadrivalent live attenuated vaccine (P = .86), according to Michael L.
The magnitude of the effect estimates reported in Table 3 and the effect estimates for additional sensitivity analyses reported in the original manuscript were also generally attenuated.
Bristol-Myers Squibb Company will evaluate its Immuno-Oncology (I-O) agent Opdivo (nivolumab) with Janssen's Live Attenuated Double-Deleted (LADD) Listerial monocytogenes cancer immunotherapy, expressing mesothelin and EGFRvIII (JNJ-64041757) in patients with non-small cell lung cancer (NSCLC).
Big Ear's new dual filter system features the normal attenuated filter along with a second non-linear filter.
In a conventional meltblown process, we have a single row of nozzles emerging a plurality of molten polymer filaments that are attenuated using hot high speed air slots.
The current study was conducted to prepare and evaluate the efficacy of live attenuated vaccine of IBH-HPS in broiler birds in Pakistan.