Pathogenicity of attenuated
IBH-HPS virus was tested in 80 broiler birds of 15 days old, reared in the Animal House of Institute of Microbiology.
Our further research illustrated that MSC infusion significantly attenuated
the degree of PMN pulmonary sequestration and NE release induced by impropriate ventilation as well as inflammatory chemokines and cytokines (including TNF-a, IL-6 and MIP-2), and do not affect the IL-10s (one type of anti-inflammatory cytokine), which consisted with previous VILI research.
In a study of rhesus macaque monkeys given attenuated
SIV, the simian counterpart to HIV, the vaccine killed off many of the monkeys that received it.
This notion is supported by findings that systemic immunization with attenuated
macaque-specific Simian immunodeficiencv virus induced virus-specific CTL responses in gut-associated lymph nodes and limited superinfection following mucosal challenge (33).
What's more, the work "fortifies the idea that you can have an attenuated
virus in an individual without causing disease.
Louis wanted to know if, in the close confines of a day care environment, the live, attenuated
virus used in a chicken pox vaccine (not yet on the market) could jump from a vaccinated child to a nonvaccinated child.
In addition to standard fiber optic patch cords and attenuated
test cables, Timbercon has pioneered proprietary products, many of which are now considered to be an industry benchmark.
The Company is building a pipeline of next generation cancer immunotherapies by combining its proprietary attenuated
Listeria vaccine platform with promising disease antigens.
The presentation highlights the application of a technology platform for the use of attenuated
autologous autoreactive T-cells for vaccinations in T-cell mediated autoimmunity.
Rotarix(R) is an oral, two-dose, live attenuated
vaccine against rotavirus disease in infants that was licensed in 1997 by AVANT Immunotherapeutics to GSK for worldwide commercialization.
The anti-hyperglycemic capabilities of PSN010 have been confirmed in several diabetic rodent models and maximal glucose concentrations were significantly attenuated
by the drug candidate.
Advances in the identification of people with attenuated
psychotic symptoms, a group generally at increased risk for psychosis, have allowed for the development of novel intervention strategies.