attenuated


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Related to attenuated: Attenuated total reflectance

attenuated

[əten′yo̅o̅·ā′tid]
Etymology: L, attenuare, to make thin
pertaining to the dilution of a solution or the reduction in virulence or toxicity of a microorganism or a drug by weakening it.

attenuated

adjective Medtalk
1. Reduced in virulence or infectivity.
2. Thin, minimal, markedly reduced or decreased.

attenuated

Weakened or reduced, and so altered in characteristics so as no longer to be dangerous. The term is applied to organisms that have been specially cultured so as to reduce their virulence and make them suitable for use in vaccines.

Attenuated

Alive but weakened; an attenuated microorganism can no longer produce disease.
Mentioned in: Tuberculin Skin Test

attenuated

having undergone a process of attenuation.

attenuated breath sounds
normal breath sounds audible via a stethoscope over the lungs.
References in periodicals archive ?
Although the quadrivalent live attenuated vaccine remains licensed in the United States, the [Advisory Committee on Immunization Practices] did not recommend this vaccine for the 2016-2017 influenza season," the investigators wrote.
Live Attenuated Influenza Vaccine is sold as FluMist Quadrivalent and is produced by AstraZeneca subsidiary, MedImmune.
The The spun-blown process has a multi-row spinnerette similar to spunbond technology but the filaments are attenuated at the nozzle's tip using high speed air similar to the meltblown process.
Keywords: Inclusion body hepatitis hydro pericardium syndrome; Vero cell line; Live attenuated vaccine; Cytopathogenic effect
MSC administration attenuated the VT20 induced increased intracellular NE activity of PMN, intracellular ROS production of PMN and serum ROS either in blood or BALF.
Despite the fact that at least 50% of people who ultimately develop schizophrenia report attenuated psychotic symptoms in adolescence, psychosis tends to be considered an "adult" disorder.
Cho KH, Caparon MG (2008) tRNA modification by GidA/MnmE is necessary for Streptococcus pyogenes virulence: a new strategy to make live attenuated strains.
In this low-risk hypothetical population, under a wide range of assumptions, the live attenuated vaccine was projected to avert more episodes of influenza, influenza-related hospitalizations, and deaths than was the inactivated vaccine.
Vaccinating a pregnant woman with the live attenuated BCG vaccine is generally not recommended, but may be indicated if the woman works in a setting where many patients are infected with resistant strains of TB.
Attenuated influenza produced by experimental intranasal inoculation.
Baseline and poststress cortisol responses were significantly attenuated among the infants of the depressed mothers, compared with those of nondepressed mothers.
In contrast to live attenuated vaccines, only a small portion of the genetic material will be used, therefore there is no risk that the vaccine could mutate or combine with naturally occurring influenza viruses to produce new strains, or recombine with human influenza strains which would have devastating global consequences.