atrophic vaginitis


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.
Note: This page may contain terms or definitions that are offensive or inappropriate for some readers.

vaginitis

 [vaj″ĭ-ni´tis]
1. inflammation of any sheathlike structure.
2. inflammation of the vagina; called also colpitis.

Etiology. Inflammation of the vaginal mucosa is invariably related to a disturbance in normal vaginal physiology. A healthy vagina depends on (1) normal estrogen secretion to maintain a thick squamous epithelium containing glycogen and (2) chemical reactions beginning with the glycogen thus available. The glycogen stimulates the growth of lactobacilli, which are beneficial normal vaginal flora that metabolize glycogen to form lactic acid. The lactic acid maintains vaginal acidity at a pH of 4.0 to 4.5.



Tampons, condoms, neglected diaphragms, and irritating douches or deodorant sprays can upset the vagina's environmental balance and produce abnormal vaginal discharge. Hyperglycemia and antibiotics can also disturb this balance. However, infectious agents are the most common cause of vaginitis; these include Trichomonas and Candida. (See also bacterial vaginosis.) Characteristics of these types of vaginitis and medical treatment and nursing intervention are summarized in the accompanying table.
Patient Education. Patients with infectious vaginitis need to know the purpose and importance of diagnostic testing and examination to verify a diagnosis, the specific type of infection or infections thus identified, and changes that may need to be made in their sexual activity to avoid reinfection. Sexual intercourse is avoided while active symptoms are present. Concurrent treatment of the partner is often necessary to avoid cyclic reinfection of one another. Condoms are encouraged because they can provide both the man and woman with some protection against sexually transmitted diseases.



In regard to prescribed treatment, the patient should be instructed to take all of the medication exactly as prescribed; a follow-up examination and testing may be necessary. If the woman has a cervical Pap smear done while she has vaginitis, there may be an abnormal test result.
adhesive vaginitis atrophic vaginitis with ulceration and exfoliation of the mucosa result in adhesions of the membranes; opposite surfaces may adhere to each other, causing obliteration of the vaginal canal. Called also senile vaginitis.
atrophic vaginitis vaginitis occurring in postmenopausal women, associated with estrogen deficiency. The two most common types are senile vulvovaginitis and adhesive vaginitis.
Candida vaginitis (candidal vaginitis) vulvovaginal candidiasis.
desquamative inflammatory vaginitis a form resembling atrophic vaginitis but affecting women with normal estrogen levels.
emphysematous vaginitis inflammation of the vagina and adjacent cervix, characterized by numerous asymptomatic, gas-filled cystlike lesions.
senile vaginitis adhesive vaginitis.

a·troph·ic vag·i·ni·tis

thinning and atrophy of the vaginal epithelium, usually resulting from diminished estrogen stimulation; a common occurrence in postmenopausal women.

atrophic vaginitis

Noninfectious inflammation of the vaginal mucosa secondary to epithelial thinning, with loss of elasticity of the vaginal wall. It is common in postmenopausal women and caused by decreased endogenous oestrogen; it may also occur after hysterectomy and radiotherapy.

Clinical findings
Pruritus ± burning sensation, reduced vaginal secretions, dyspareunia, post-coital bleeding, ±bacterial infection.
 
Management
Topical and/or oral oestrogen (contraindicated in patients with prior breast or endometrial cancer).

atrophic vaginitis

Gynecology A condition characterized by postmenopausal inflammation of vaginal mucosa 2º to thinning, with loss of elasticity of the vaginal wall, common in postmenopausal ♀ due to ↓ endogenous estrogen Clinical Pruritus ± burning sensation, ↓ in vaginal secretions, dyspareunia, post-coital bleeding, ±bacterial infection Treatment Topical and/or oral estrogen–contraindicated in Pts with prior breast or endometrial CA. See Lichen sclerosis.

a·troph·ic vag·i·ni·tis

(ā-trō'fik vaj'i-nī'tis)
Thinning and atrophy of the vaginal epithelium usually resulting from diminished estrogen stimulation; a common occurrence in postmenopausal women.
References in periodicals archive ?
* The report reviews pipeline therapeutics for Vaginal Atrophy (Atrophic Vaginitis) by companies and universities/research institutes based on information derived from company and industry-specific sources
He and his coworkers recently completed an as-yet unpublished phase III clinical trial of pilocarpine (Salagen) for atrophic vaginitis based on a favorable preliminary report in patients with Sjogren syndrome.
Gathering a clinical history, a physical exam, and urinalysis can identify hematuria, atrophic vaginitis and bladder infection, or constipation.
(%) Low-grade squamous 632 (70.4) intraepithelial lesion Negative for intraepithelial 122 (13.6) lesion or malignancy Reparative changes 90 (10.0) Trichomonas vaginitis 15 (1.7) Cellular changes consistent 13 (1.4) with herpes simplex virus Atrophic vaginitis 12 (1.3) Fungal organisms consistent 11 (1.2) with Candida species Follicular cervicitis 3 (0.3) Total 898 (100)
All of the women were on an adjuvant aromatase inhibitor or selective estrogen receptor modulator and had been using a vaginal estrogen for an average of 20 months to treat severe atrophic vaginitis. Fourteen women were using one vaginal estrogen tablet (Vagifem) inserted twice weekly, and 10 were using the vaginal estradiol ring (Estring), inserted every 3 months.
Previously, all 24 patients on vaginal estrogens had unsuccessfully tried all the other methods of improving atrophic vaginitis. They were still suffering, and vaginal estrogens were the only option left, Dr.
The Food and Drug Administration has approved a 10-mcg dose of estradiol in vaginal tablet form to treat atrophic vaginitis associated with menopause.
2 December 2009 - Denmark-based healthcare company Novo Nordisk A/S (NYSE: NVO) said today that the US Food and Drug Administration (FDA) has approved a 10 mcg dose formulation of Vagifem (estradiol vaginal tablets) for the treatment of atrophic vaginitis due to menopause.
The causes of transient incontinence are easily remembered using the mnemonic DIAPPERS (delirium, urinary infection, atrophic vaginitis, pharmaceuticals, psychological problem, excess urine output, restricted mobility, stool impaction) coined by Resnick (Resnick, 1984).
Few would dispute the inappropriateness of subjecting a bedridden end-stage Alzheimer's patient to a pelvic examination to rule out atrophic vaginitis. The attitude that it's pointless to try to change the continency status of a 90-year-old nursing home resident is prevalent, but needs to be changed.
[USPRwire, Wed Dec 30 2015] Global Markets Direct's, 'Vaginal Atrophy (Atrophic Vaginitis) - Pipeline Review, H2 2015', provides an overview of the Vaginal Atrophy (Atrophic Vaginitis)'s therapeutic pipeline.