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Related to atriopeptin: atrial natriuretic factor


a peptide hormone that promotes the loss of fluid and electrolytes and the reduction of vascular tone.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

a·tri·al na·tri·u·ret·ic pep·tide (ANP),

a 28-amino acid peptide (α-ANP) derived from cardiac atria, several smaller fragments of α-ANP, and a dimer of α-ANP with 56 amino acids (β-ANP) that are present in plasma in heart failure. Among other actions, ANP promotes renal salt and water excretion, increases capillary function, and decreases arterial pressure and the secretion of renin, angiotensin, aldosterone, and antidiuretic hormone.
Farlex Partner Medical Dictionary © Farlex 2012


A gene on chromosome 1p36.21 that encodes a member of the natriuretic peptide family, which control extracellular fluid volume and electrolyte homeostasis.
Molecular pathology
NPPA mutations are associated with atrial fibrillation familial type 6.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.


A hormone stored in the muscle cells of the atria of the HEART and released into the blood when the blood volume increases beyond the optimum. Atriopeptin increases the rate of urine production and salt excretion. The discovery of atriopeptin led to the realization that this was one of a family of small peptides, called the atrial natriuretic peptides (ANPs), with receptors in the heart, lungs, kidneys, bone marrow, thymus and brain. ANPs have amino acid sequences of from 28 to 53 moieties.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
References in periodicals archive ?
Morris, "Effect of intravenous infusion of atriopeptin 3 on immediate renal allograft function," Kidney International, vol.
Another hormone affecting sodium reabsorption is atrial natriuretic hormone (ANH), also known as atrial natriuretic peptide, atrial natriuretic factor, or atriopeptin. ANH is secreted from the cells in the cardiac atria in response to distention of the atria, secondary to plasma volume expansion.