atovaquone


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atovaquone

 [ah-to´vah-kwōn]
an antibiotic used in treatment of mild to moderate Pneumocystis cariniipneumonia and the prevention and treatment of falciparum malaria; administered orally.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

atovaquone

(ə-tō′və-kwōn′)
n.
A drug, C22H19ClO3, used to treat pneumonia caused by pneumocystis fungi and, in combination with proguanil, to prevent or treat malaria.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

atovaquone

An agent used for treating mild to moderate Pneumocystis jiroveci (carinii) pneumonia in patients with HIV infection, and for salvage treatment of toxoplasmosis and microsporidiosis.
 
Pros
Less toxic, more tolerable than trimethoprim-sulfamethoxazole (TMP-SMX).

Cons
Less effective than TMP-SMX.
 
Adverse effects
Headache, nausea, diarrhoea, fever, rashes.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

atovaquone

Mepron Infectious disease An agent used for treating PCP in Pts with HIV infection and for toxoplasmosis and microsporidiosis Pros Less toxic, more tolerable than T-S Cons Less effective than T-S Adverse effects Headache, nausea, diarrhea, fever and rashes. See AIDS, Pneumocystis cariniipneumonia, Trimethoprim–Sulfamethoxazole.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

Atovaquone

A drug used in the treatment of MALARIA and TOXOPLASMOSIS. Brand names are Wellvone and, in combination with proguanil, Malarone.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
References in periodicals archive ?
Although atovaquone is the only safe alternative agent for which efficacy and safety have been relatively well established, it has been proven to be less potent than standard therapies (5).
Ancak hastamizin tedavi altinda devam eden trombositopeni ve lokopenisi olmasi nedeniyle, artemether bilesigine yanitsiz olan rekrudesens dusunulerek tedavi atovaquone ile degistirildi ve tedavi sonucunda hizla klinik duzelme goruldu.
If engraftment is delayed and TMP/SMX cannot be given due to myelosuppression, atovaquone [27] can be used until engraftment, followed by TMP/SMX.
Ito, "Reversible cerebral vasoconstriction syndrome due to atovaquone," Case Reports in Neurology, vol.
While quinine was isolated from the bark of the cinchona tree in 1820, chloroquine, proguanil, mefloquine, and atovaquone each were developed during or after a military conflict during 1945-1985.
The patient was diagnosed with babesiosis and admitted to the hospital, where he was treated with atovaquone, azithromycin, and doxycycline.
Decoquinate is structurally distinct to atovaquone, which is broadly used for malaria prophylaxis and treatment, and decoquinate demonstrates limited cross-resistance to atovaquone-resistant parasites [3].
vivax [7], numerous publications reported on the antiplasmodial activity of naphthoquinones leading to the development of atovaquone (3, Figure 1), a totally synthetic hydroxy-1,4-naphthoquinone [4].
After laboratory confirmation of malaria diagnosis, the therapy was changed to a 3-day course of atovaquone and proguanil.
Primary treatment is Atovaquone and Zithromax given for seven days.
These cells were sensitive to an antimalarial drug called atovaquone; chemical maturation through exposure to small molecules also made the cells sensitive to another antimalarial drug called primaquine, demonstrating the value of this approach for testing new antimalarial drugs.