atosiban


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atosiban

A competitive OXYTOCIN receptor antagonist used to quieten a uterus contracting at an undesirably early stage of gestation and allow greater maturation of the fetus before birth. A brand name is Tractocile.
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In the PROLONG trial, OBE022 or matching placebo is administered daily for 7 days to pregnant women who are receiving an infusion of atosiban for 48 hours, the current standard of care therapy for preterm labor in the countries in which the PROLONG trial is being conducted.
This report studies the global market size of Atosiban in key regions like North America, Europe, Asia Pacific, Central & South America and Middle East & Africa, focuses on the consumption of Atosiban in these regions.
centralized procurement of medicines for ropivacaine (doe), Calcium folate (doe), Human fibrinogen (doe) and human thrombin (doe), Doxorubicin (doe) liposomal, Paricalcitol (doe) and atosiban (doe) ) for all osakidetza service organizations and health centers of private ownership and non-profit making, Located in the autonomous community of euskadi, Within the framework provided in article 30 of law 8/1997, Of june 26, Sanitary management of euskadi, That sign an agreement of connection with osakidetza / basque health service
Recent studies have shown that oxytocin receptor inhibitors (atosiban) may also be effective.
The nitroglycerine infusion was interrupted at the end of the hysterorrhaphy, and a bolus dose of atosiban 6.75 mg was administered followed by a 300[micro]g/minute infusion.
[32] described a case of maternal atrial fibrillation after sequential use of nifedipine and atosiban for the treatment of preterm labor.
Paciente de 45 anos, sextigesta, con embarazo de alto riesgo por insuficiencia renal cronica materna, que ingresa en hospital regional, procedente de hospital comarcal, por amenaza de parto prematuro en semana 27+2, con tratamiento tocolitico (Atosiban) en tercer paso (8 ml/h).
Dentro del grupo de los antagonistas peptidicos se encuentra el d[DTyr(Et)2,Thr4]OVT, conocido comercialmente como Atosiban (Manning et al., 2012) y caracterizado por tener afinidad tambien con los receptores de V1A de vasopresina (AVP) y metabolizarse de forma rapida (Viero et al., 2010).
These tocolytic agents include atosiban, magnesium sulphate, betamimetics, calcium channel blockers, nitric oxide donors.
SAN DIEGO -- Nifedipine and atosiban for tocolysis in women with threatened preterm delivery had similar rates of adverse perinatal outcomes in a randomized clinical trial, but an increase in perinatal mortality in those treated with nifedipine is raising concerns about its safety.
Atosiban has lower maternal complications and a higher price as compared to [beta]2 agonists.
The probability of delivery being delayed by 48 hours was greatest with prostaglandin inhibitors (odds ratio [OR], 5.39; 95% confidence interval [CI], 2.14-12.34), followed by magnesium sulfate (OR, 2.76; 95% CI, 1.58-4.94), calcium channel blockers (OR, 2.71; 95% CI, 1.17-5.91), beta mimetics (OR, 2.41; 95% CI, 1.27-4.55), and the oxytocin receptor blocker atosiban (OR, 2.02; 95% CI, 1.10-3.80), compared with placebo.