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an agent that inhibits cholesterol synthesis, used as the calcium salt in treatment of primary hypercholesterolemia and hyperlipidemia; administered orally.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
A statin, (C33H34FN2O5)2Ca·3H2O, that blocks the body's synthesis of cholesterol and is used to treat hyperlipidemia.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
atorvastatinA cholesterol-lowering HMG-CoA reductase inhibitor, or statin, which improves the lipid profile—LDL-C reduced 35% to 60%; TGs reduced 20–37%; HDL-C increased 5–9%.
Liver dysfunction, rhabdomyolysis with acute renal failure secondary to myoglobinuria, constipation, flatulence, dyspepsia, abdominal pain, myalgia, weakness.
Homozygous familial hypercholesterolaemia, severe refractory hypercholesterolaemia.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
atorvastatinLipitor® Cardiology A cholesterol-lowering HMG-CoA reductase inhibitor or statin which improves the lipid profile–↓ 35% to 60% LDL-C; ↓TGs 20–37%;↑ 5–9% HDL-C Adverse effects Liver dysfunction, rhabdomyolysis with acute renal failure 2º to myoglobinuria, constipation, flatulence, dyspepsia, abdominal pain, myalgia, weakness. See AVERT, Statin.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
atorvastatinA cholesterol-lowering drug. A brand name is Lipitor. See STATINS.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005