atherosclerotic plaque


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atherosclerotic plaque

The core lesion of atherosclerosis, beginning as a fatty streak (an ill-defined yellow lesion­, or fatty plaque), which develops well-demarcated edges that evolve to fibrous plaques (whitish lesions with a grumous lipid-rich core). With time, it becomes a complicated plaque composed of WBCs, smooth muscle cells and extracellular matrix in larger artery intimas.

atherosclerotic plaque

Cardiology The core lesion of atherosclerosis; it begins as a fatty streak, an ill-defined yellow lesion–fatty plaque, which develops well-demarcated edges that evolve to fibrous plaques, whitish lesions with a grumous lipid-rich core which, with time, becomes a complicated plaque composed of WBCs, smooth muscle cells and extracellular matrix in large artery intimas. See Complicated plaque.

Atherosclerotic plaque

A deposit of fat and other substances that accumulate in the lining of the artery wall.
Mentioned in: Atherectomy
References in periodicals archive ?
The switch from anti-inflammatory lipocalin-type prostaglandin D synthase to pro-inflammatory Type 1 inducible membrane-bound prostaglandin E synthase-1 (mPGES-1) in carotid atherosclerotic plaque macrophages is associated with acute brain ischemia.
In the current study, we tried to detect the correlations of high-sensitivity (hs)-CRP, intima-media thickness, atherosclerotic plaques and neurological function in patients with atherosclerotic cerebral infarction, to facilitate physicians in diagnosing atherosclerotic cerebral infarction.
The combination of the two supplements has undergone clinical trials in more than 2,000 people with atherosclerotic plaque, and has demonstrated a significant reduction, not only in plaque progression and texture, but also in prevention of new cardiovascular symptoms.
To test our hypothesis that altered collagen contents by P4H[alpha]1 overexpression affects the development of atherosclerotic plaque, we studied the development of carotid atherosclerotic lesions of vulnerable and stable phenotypes induced by a perivascular cast [14].
Apoptosis is a programmed form of cell death that occurs in all major cell types of atherosclerotic plaques where it is implicated in the development and progression of the disease [1-3].
Tissue samples were obtained from atherectomy of coronary artery or carotid atherosclerotic plaques by surgeon during CABG.
A mechanistic analysis of the role of microcalcifications in atherosclerotic plaque stability: potential implications for plaque rupture.
Pregnancy associated plasma protein-A (PAPP-A) is not a marker of the vulnerable atherosclerotic plaque.
They found that several bacteria were found in the atherosclerotic plaques and, primarily, the mouth, but also the gut, of the same patient and that the bacteria Pseudomonas luteola and Chlamydia pneumoniae were present in all atherosclerotic plaques.
Although the mean atherosclerotic plaque burden did increase with the 10-year Framingham risk, the correlation between [the FRS] and plaque was fair," Dr.
Of the patients who were found to be in the very-low- and low-risk groups, more than half had visible evidence of atherosclerotic plaque on CTA, Dr.
The process responsible for the formation of the atherosclerotic plaque starts with the accumulation of lipoprotein particles (LDL) in the intima; these lipoproteins undergo modifications that include oxidation and glycation.

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