atheromatous plaque


Also found in: Dictionary, Thesaurus, Encyclopedia.
Related to atheromatous plaque: atherosclerosis, aneurysm

plaque

 [plak]
1. any patch or flat area.
2. a superficial, solid, elevated skin lesion with a diameter equal to or greater than 1.0 cm (0.5 cm according to some authorities); see also papule.
atheromatous plaque fibrous plaque.
dental plaque a dense, nonmineralized, highly organized biofilm of microbes, organic and inorganic material derived from the saliva, gingival crevicular fluid, and bacterial byproducts. It plays an important etiologic role in the development of dental caries and periodontal and gingival diseases; calcified plaque forms dental calculus.
fibrous plaque the lesion of atherosclerosis, a white to yellow area within the wall of an artery that causes the intimal surface to bulge into the lumen; it is composed of lipid, cell debris, smooth muscle cells, collagen, and, in older persons, calcium. Called also atheromatous plaque.
Hollenhorst p's atheromatous emboli containing cholesterol crystals in the retinal arterioles.
pleural p's opaque white plaques on the parietal pleura, visible radiographically in cases of asbestosis.
senile p's microscopic lesions composed of fragmented axon terminals and dendrites surrounding a core of amyloid seen in the cerebral cortex in Alzheimer's disease.

ath·er·om·a·tous plaque

a well-demarcated yellow area or swelling on the intimal surface of an artery; produced by intimal lipid deposit.
References in periodicals archive ?
The present study analyzed adult individuals of both genders, Afro-descendants, with cardiovascular risk factors, inhabitants of Quilombola remnant communities, and found no evidence of an independent association between serum levels of 25(OH)D and C-IMT, as well as the presence of carotid atheromatous plaques. On the other hand, an independent inverse association between 25(OH)D levels and urinary albumin excretion, assessed by ACR in an isolated urine sample, was observed.
[23], in 1987, as compensatory enlargement of the coronary arteries to accommodate large quantities of atheromatous plaque, thus permitting the maintenance of blood flow.
Nevertheless, mCRP appears to play a more direct or "effector" role in atherosclerosis, in contrast to pCRP, which may be described as a "facilitator" in circulation, awaiting dissociation for focalization of proinflammatory effects to injured sites, such as atheromatous plaques [88, 93].
Another positive effect of EDTA for the treatment of atherosclerosis, CAD, CVD and CVA is its ability to reduce or eradicate stenosis due to atheromatous plaques. Studies have found that chronic exposure to low levels of lead may contribute to hypertension and the development of CVD.
The first few centimetres of these vessels are particularly susceptible to atheromatous plaque formation, resulting in cardiac muscle receiving insufficient oxygen to perform properly and thus the body does not receive a sufficient circulation.
It contains starch, unsaturated fatty acids and other natural compounds, including 10 that contain HMG-CoA reductase inhibitors, which reduce circulating LDL (often referred to as "bad") cholesterol, a substance that contributes to the formation of atheromatous plaque in blood vessels.
Artery-to-artery emboli frequently result from detachment of thrombi from the internal carotid artery at the site of an ulcerated atheromatous plaque. These detached thrombi then travel further into the cerebral circulation until they lodge into a smaller vessel.
Renovascular hypertension is the most common clinical manifestation caused by ARAS.1 Rarely, spontaneous renal artery dissection is reported to occur due to dissection of atheromatous plaque around the renal artery.5
This atheromatous plaque is prone to rupture by proinflammatory cytokines due to activation of monocytes and macrophages and is reflected by the high levels of biomarkers.
Atheromatous plaque formation in rabbit aorta fed with high cholesterol diet.
Among these mediators, histamine and leukotrienes may lead to coronary events via vasoconstriction, whereas proteases lead to coronary events via metalloprotein activation, collagen reduction, and the potential of inducing atheromatous plaque erosion.
Unlike that which is seen in atherosclerotic cardiovascular disease, there is no atheromatous plaque, typically no significant calcification and no surface ulceration with overlying thrombotic material.