The present study analyzed adult individuals of both genders, Afro-descendants, with cardiovascular risk factors, inhabitants of Quilombola remnant communities, and found no evidence of an independent association between serum levels of 25(OH)D and C-IMT, as well as the presence of carotid atheromatous plaques
. On the other hand, an independent inverse association between 25(OH)D levels and urinary albumin excretion, assessed by ACR in an isolated urine sample, was observed.
, in 1987, as compensatory enlargement of the coronary arteries to accommodate large quantities of atheromatous plaque
, thus permitting the maintenance of blood flow.
Nevertheless, mCRP appears to play a more direct or "effector" role in atherosclerosis, in contrast to pCRP, which may be described as a "facilitator" in circulation, awaiting dissociation for focalization of proinflammatory effects to injured sites, such as atheromatous plaques
Another positive effect of EDTA for the treatment of atherosclerosis, CAD, CVD and CVA is its ability to reduce or eradicate stenosis due to atheromatous plaques
. Studies have found that chronic exposure to low levels of lead may contribute to hypertension and the development of CVD.
The first few centimetres of these vessels are particularly susceptible to atheromatous plaque
formation, resulting in cardiac muscle receiving insufficient oxygen to perform properly and thus the body does not receive a sufficient circulation.
It contains starch, unsaturated fatty acids and other natural compounds, including 10 that contain HMG-CoA reductase inhibitors, which reduce circulating LDL (often referred to as "bad") cholesterol, a substance that contributes to the formation of atheromatous plaque
in blood vessels.
Artery-to-artery emboli frequently result from detachment of thrombi from the internal carotid artery at the site of an ulcerated atheromatous plaque
. These detached thrombi then travel further into the cerebral circulation until they lodge into a smaller vessel.
Renovascular hypertension is the most common clinical manifestation caused by ARAS.1 Rarely, spontaneous renal artery dissection is reported to occur due to dissection of atheromatous plaque
around the renal artery.5
This atheromatous plaque
is prone to rupture by proinflammatory cytokines due to activation of monocytes and macrophages and is reflected by the high levels of biomarkers.
formation in rabbit aorta fed with high cholesterol diet.
Among these mediators, histamine and leukotrienes may lead to coronary events via vasoconstriction, whereas proteases lead to coronary events via metalloprotein activation, collagen reduction, and the potential of inducing atheromatous plaque
Unlike that which is seen in atherosclerotic cardiovascular disease, there is no atheromatous plaque
, typically no significant calcification and no surface ulceration with overlying thrombotic material.