panhypopituitarism

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panhypopituitarism

 [pan-hi″po-pĭ-too´ĭ-tar-izm″]
generalized hypopituitarism due to absence of or damage to the pituitary gland; in its complete form it leads to absence of gonadal function, loss of secondary sex characters, and insufficiency of thyroid and adrenal function. When cachexia is a prominent feature, it is called simmonds' disease.

pan·hy·po·pi·tu·i·tar·ism (PHP),

(pan-hī'pō-pi-tū'i-tăr-izm), [MIM*312000]
A state in which the secretion of all anterior pituitary hormones is inadequate or absent; caused by a variety of disorders that result in destruction or loss of function of all or most of the anterior pituitary gland. Rare forms of PHP are inherited as autosomal recessive [MIM*262600] or as X-linked recessive [MIM*312000].

Sheehan syndrome

A condition that follows postpartum uterine haemorrhage severe enough to cause circulatory collapse, resulting in pituitary necrosis and hypopituitarism, especially if disseminated intravascular coagulation (DIC) was also present.

Clinical findings
Galactorrhoea, amenorrhoea or oligomenorrhoea, secondary hypothyroidism, cold intolerance, hypotension, bradycardia, weight gain, hair loss, adrenal insufficiency, fatigue, loss of libido, hypoglycaemia, hyponatraemia.

panhypopituitarism

Pituitary dwarfism, see there.

pan·hy·po·pi·tu·i·tar·ism

(PHP) (pan-hī'pō-pi-tū'i-tă-rizm)
A state in which the secretion of all anterior pituitary hormones is inadequate or absent.
Synonym(s): hypophysial cachexia.

Panhypopituitarism

Generalized decrease of all of the anterior pituitary hormones.
Mentioned in: Pituitary Dwarfism

pan·hy·po·pi·tu·i·tar·ism

(pan-hī'pō-pi-tū'i-tă-rizm) [MIM*312000]
A state in which secretion of all anterior pituitary hormones is diminished.
Synonym(s): hypophysial cachexia.