asymmetrical dimethylarginine

asymmetrical dimethylarginine

(dī″meth″ĭl-ar′jĭ-nēn″)
An endogenous inhibitor of nitric acid synthase, an enzyme found in endothelial cells. Its concentration is elevated in patients with chronic kidney disease. It has been proposed as a biomarker of and risk factor for cardiovascular disease.
References in periodicals archive ?
Blood was centrifuged for blood sugar, glycosylated haemoglobin, total cholesterol, high-density lipoprotein, low-density lipoprotein, triglyceride and asymmetrical dimethylarginine.
LDL cholesterol upregulates synthesis of asymmetrical dimethylarginine in human endothelial cells: Involvement of S-adenosylmethionine-dependent methyltransferases.
Plasma concentration of asymmetrical dimethylarginine and mortality in patients with end-stage renal disease: a prospective study.
They also measured increases in plasma nitric oxide levels and decreases in asymmetrical dimethylarginine, thiobarbituric acid reactive substance, soluble Fas ligand, soluble CD40 ligand, tumor necrosis factor-alpha, interleukin (IL)-6 and IL-8.
In the past 15 years, scientists mainly focused on asymmetrical dimethylarginine (ADMA), the most potent endogenous nitric oxide (NO) synthase inhibitor.
Determination of asymmetrical dimethylarginine by capillary electrophoresis-laser-induced fluorescence.
In that clinical study, effects of nebivolol and metoprolol on serum asymmetrical dimethylarginine (ADMA) levels, an indicator of endothelial dysfunction, were compared.
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