"Furthermore, dubious extras not regulated by HFEA such as endometrial scratching, assisted hatching
, and embryo glue that lack strong evidence of effectiveness often add another PS3,500 for each cycle.
There appeared to be no association with specific IVF treatments, whether children were conceived by donor egg versus autologous egg; frozen embryos versus fresh embryos; use of intracytoplasmic sperm injection (ICSI) versus none; assisted hatching
versus none; and day-3 versus day-5 transfer.
Then there's 'add ons' such as endometrial scratching, assisted hatching
and embryo glue - which aren't regulated by the Human Fertilisation and Embryology Authority and lack strong evidence of effectiveness.
The exclusion criteria were body mass index (BMI) >30 kg/[m.sup.2], presence of any untreated thyroid dysfunction/hyperprolactinemia, diminished ovarian reserve according to the Bologna criteria (14) or premature ovarian failure, uterine abnormality, positive tests for antinuclear, anti-double-stranded DNA, anticardiolipin antibodies or lupus anticoagulant, male factor infertility, endometriosis, frozen-thaw cycles, cycles managed with assisted hatching
, and cycles with day 5 embryo transfer (ET).
The probable need for assisted hatching
appeared to be decreased mobility due to multiple deformities.
Most fertility specialists believe that in more than 95% of IVF failures it is due to arrest of the embryos With the advancements in technology, the field of the Laser Assisted Hatching
(AH) a technology which helps embryos to attach to the womb of the woman - has emerged as an art that gives best possible results.
The facility also offers egg and embryo donation, assisted hatching
, sperm bank, and surrogacy options, among others.
Embryo transfer was recorded, together with other procedures such as assisted hatching
and vitrification of supernumerary embryos.
A Dutch embryologist, Jacques Cohen, published the first report on assisted hatching
in human embryos (51).
Through the 'IVF Suraksha' scheme, members are assured of two IVF - ICSI, three to five frozen embryo transfers, blastocyst transfer, assisted hatching
and freezing of extra embryos.
Another embryo manipulation technique that has raised concern is "assisted hatching
" (Alikani et al.