asporin

asporin

A protein found in the extracellular matrix that decreases cartilage production and the accumulation of proteoglycans.
References in periodicals archive ?
Asporin is a member of the sub family of small leucine-rich proteoglycans that also includes decorin and biglycan.
Expression pattern and gene characterization of asporin.
Binding characteristics of the osteoarthritis-associated protein asporin.
Mechanisms for asporin function and regulation in articular cartilage.
An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis.
Expression and regulation of the osteoarthritis-associated protein asporin.
TABLE 1: FACTORS REGULATING PERIODONTAL LIGAMENT HOMEOSTASIS Cellular Factors Biochemical Factors Genetic Mechanical Factors Factors * Mesenchymal stem * Osteocalcin * Runx2 cells * Bone sialoprotein * Msx2 * Epithelial cell * Glycosaminoglycans * Twist gene rests * Osteonectin * Fibroblasts * Nitrous oxide * Osteoprotegrin * Prostaglandins * Cytokines * Growth Factors * Periostin * S100A4 * RGD-CAP * Asporin
Mass spectrometryanalysis of tissue extracts identified only 5 of the candidate biomarkers in the samples analyzed: apolipoprotein C1 (APOC1, gel 8), asporin (ASPN, gel 5), complement C4A (gel 8), 6-phosphogluconolactonase (PGLS, gel 7), and ribosomal protein L22-like 1 (RPL22L1, gel 8).
5 Diff Exp 4 ASPN Asporin 433 Diff Exp 5 B3GNT6 UDP-GlcNAc:betaGal 42.
15 PRELP CAG47066 XM_001630052 2e-15 Other extracellular matrix proteins Agrin CAI15575 XM_001632399 3e-75 Asporin CAI16697 XM_001638871.
However, we failed to identify asporin, fibronectin, matrilin, osteomodulin, podocan, reelin, or vitronectin in any protostome animals, suggesting that these ECM proteins may have originated within the Deuterostomia.
protostome) using human genes implicated in wound healing in the initial query Extracellular matrix ID Protostome E proteins hit value Human query SLRPs (small leucine-rich-repeal proteins) Biglycan AAA52287 XM_001649763 3e-21 Chondroadherin AAK51556 XM_970227 3e-26 Decorin AAB60901 No match n/a Fibrinidulin CAA53233 AJ549813 9e-21 Keratocan NP_008966 XM_001650288 8e-16 Lumican AAA91639 XM_395331 3e-17 Opticin CAB53459 XM_001606218 4e-11 Osteoglyein CAI16695 NM_206253 4e-04 PRELP CAG47066 XM_001360484 2e-15 Other extraceluar matrix proteins Asporin CAI16697 XM_967172 2e-28 Dermatan Sulf.